Sequence Detail

ID/Version

Q9R1B9 E9QKB4 Q9Z166 (UniProt | EBI)

Last sequence update: 2011-07-27
Last annotation update: 2024-03-27

Sequence description from provider

RecName: Full=Slit homolog 2 protein; Short=Slit-2;Contains: RecName: Full=Slit homolog 2 protein N-product;Contains: RecName: Full=Slit homolog 2 protein C-product;Flags: Precursor;

Provider

SWISS-PROT

Sequence

Polypeptide 1521 aa

Source

Organism mouse

See UniProt | EBI for source

Annotated genes and markers

Follow the symbol links to get more information on the GO terms, expression assays, orthologs, phenotypic alleles, and other information for the genes or markers below.

Type	Symbol	Name	GO Terms	Expression Assays	Orthologs	Phenotypic Alleles
Gene	Slit2	slit guidance ligand 2	92	140	3	15

Sequence references in MGI

J:52200 Holmes GP, et al., Distinct but overlapping expression patterns of two vertebrate slit homologs implies functional roles in CNS development and organogenesis. Mech Dev. 1998 Dec;79(1-2):57-72
J:56938 Yuan W, et al., The mouse SLIT family: secreted ligands for ROBO expressed in patterns that suggest a role in morphogenesis and axon guidance. Dev Biol. 1999 Aug 15;212(2):290-306
J:63171 Niclou SP, et al., Slit2 is a repellent for retinal ganglion cell axons. J Neurosci. 2000 Jul 1;20(13):4962-74
J:63172 Erskine L, et al., Retinal ganglion cell axon guidance in the mouse optic chiasm: expression and function of robos and slits. J Neurosci. 2000 Jul 1;20(13):4975-82
J:107695 Bagri A, et al., Slit proteins prevent midline crossing and determine the dorsoventral position of major axonal pathways in the mammalian forebrain. Neuron. 2002 Jan 17;33(2):233-48
J:109226 Nguyen-Ba-Charvet KT, et al., Slit1 and slit2 proteins control the development of the lateral olfactory tract. J Neurosci. 2002 Jul 1;22(13):5473-80