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Sequence Detail
Q9EQZ7 Q8C433 Q8CCK2 (UniProt | EBI) Last sequence update: 2001-03-01
Last annotation update: 2019-12-11
from provider
RecName: Full=Regulating synaptic membrane exocytosis protein 2;AltName: Full=Rab-3-interacting molecule 2; Short=RIM 2;AltName: Full=Rab-3-interacting protein 2;
Polypeptide 1530 aa
For this sequence
Organism mouse
See UniProt | EBI for source
Annotated genes and markers Follow the symbol links to get more information on the GO terms, expression assays, orthologs, phenotypic alleles, and other information for the genes or markers below.
Type Symbol Name GO Terms Expression
Orthologs Phenotypic
Gene Rims2 regulating synaptic membrane exocytosis 2 58 4 7 171
Sequence references in MGI J:71886 Ozaki N, et al., cAMP-GEFII is a direct target of cAMP in regulated exocytosis. Nat Cell Biol. 2000 Nov;2(11):805-11
J:81000 Fujimoto K, et al., Piccolo, a Ca2+ sensor in pancreatic beta-cells. Involvement of cAMP-GEFII.Rim2.Piccolo complex in cAMP-dependent exocytosis. J Biol Chem. 2002 Dec 27;277(52):50497-502
J:82469 Wang Y, et al., Genomic definition of RIM proteins: evolutionary amplification of a family of synaptic regulatory proteins( small star, filled ). Genomics. 2003 Feb;81(2):126-37
J:83108 Fukuda M, Distinct Rab binding specificity of Rim1, Rim2, rabphilin, and Noc2. Identification of a critical determinant of Rab3A/Rab27A recognition by Rim2. J Biol Chem. 2003 Apr 25;278(17):15373-80
J:99680 The FANTOM Consortium and RIKEN Genome Exploration Research Group and Genome Science Group (Genome Network Project Core Group), The Transcriptional Landscape of the Mammalian Genome. Science. 2005;309(5740):1559-1563
J:263376 Trinidad JC, et al., Comprehensive identification of phosphorylation sites in postsynaptic density preparations. Mol Cell Proteomics. 2006 May;5(5):914-22

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
MGI 6.14
The Jackson Laboratory