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Sequence Detail
ID/Version
Q9DBD2 (UniProt | EBI) Last sequence update: 2001-06-01
Last annotation update: 2024-03-27
Sequence
description
from provider
RecName: Full=E3 ubiquitin-protein ligase MARCHF8; EC=2.3.2.27;AltName: Full=Cellular modulator of immune recognition; Short=c-MIR;AltName: Full=Membrane-associated RING finger protein 8;AltName: Full=Membrane-associated RING-CH protein VI
Provider SWISS-PROT
Sequence
Polypeptide 286 aa
For this sequence
Source
Organism mouse
See UniProt | EBI for source
Annotated genes and markers Follow the symbol links to get more information on the GO terms, expression assays, orthologs, phenotypic alleles, and other information for the genes or markers below.
Type Symbol Name GO Terms Expression
Assays
Orthologs Phenotypic
Alleles
Gene Marchf8 membrane associated ring-CH-type finger 8 27 96 3 31
Sequence references in MGI J:99680 The FANTOM Consortium and RIKEN Genome Exploration Research Group and Genome Science Group (Genome Network Project Core Group), The Transcriptional Landscape of the Mammalian Genome. Science. 2005;309(5740):1559-1563
J:134430 Ohmura-Hoshino M, et al., Inhibition of MHC class II expression and immune responses by c-MIR. J Immunol. 2006 Jul 1;177(1):341-54
J:341074 Yang X, et al., MARCH8 attenuates cGAS-mediated innate immune responses through ubiquitylation. Sci Signal. 2022 May 3;15(732):eabk3067

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
05/28/2024
MGI 6.13
The Jackson Laboratory