Sequence Detail

ID/Version

Q99PF4 Q5QGS3 Q5QGS7 Q5QGS8 E9QP63 Q99NH1 Q5QGS4 Q9D4N9 (UniProt | EBI)

Last sequence update: 2011-07-27
Last annotation update: 2024-03-27

Sequence description from provider

RecName: Full=Cadherin-23;AltName: Full=Otocadherin;Flags: Precursor;

Provider

SWISS-PROT

Sequence

Polypeptide 3354 aa

Source

Organism mouse

See UniProt | EBI for source

Annotated genes and markers

Follow the symbol links to get more information on the GO terms, expression assays, orthologs, phenotypic alleles, and other information for the genes or markers below.

Type	Symbol	Name	GO Terms	Expression Assays	Orthologs	Phenotypic Alleles
Gene	Cdh23	cadherin related 23 (otocadherin)	63	110	3	48

Sequence references in MGI

J:66698 Di Palma F, et al., Mutations in cdh23, encoding a new type of cadherin, cause stereocilia disorganization in waltzer, the mouse model for usher syndrome type 1D. Nat Genet. 2001 Jan;27(1):103-7
J:69985 Wilson SM, et al., Mutations in Cdh23 Cause Nonsyndromic Hearing Loss in waltzer Mice. Genomics. 2001 Jun 1;74(2):228-33
J:73941 Di Palma F, et al., Genomic structure, alternative splice forms and normal and mutant alleles of cadherin 23 (Cdh23). Gene. 2001 Dec 27;281(1-2):31-41
J:98268 Lagziel A, et al., Spatiotemporal pattern and isoforms of cadherin 23 in wild type and waltzer mice during inner ear hair cell development. Dev Biol. 2005 Apr 15;280(2):295-306
J:99680 The FANTOM Consortium and RIKEN Genome Exploration Research Group and Genome Science Group (Genome Network Project Core Group), The Transcriptional Landscape of the Mammalian Genome. Science. 2005;309(5740):1559-1563
J:125331 Kazmierczak P, et al., Cadherin 23 and protocadherin 15 interact to form tip-link filaments in sensory hair cells. Nature. 2007 Sep 6;449(7158):87-91
J:192825 Sotomayor M, et al., Structure of a force-conveying cadherin bond essential for inner-ear mechanotransduction. Nature. 2012 Dec 6;492(7427):128-32
J:245265 Elledge HM, et al., Structure of the N terminus of cadherin 23 reveals a new adhesion mechanism for a subset of cadherin superfamily members. Proc Natl Acad Sci U S A. 2010 Jun 08;107(23):10708-12
J:292518 Huttlin EL, et al., A tissue-specific atlas of mouse protein phosphorylation and expression. Cell. 2010 Dec 23;143(7):1174-89