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Sequence Detail
Q99N32 Q99N31 Q920J2 B2RQN8 (UniProt | EBI) Last sequence update: 2001-06-01
Last annotation update: 2019-12-11
from provider
RecName: Full=Beta-klotho; Short=BKL; Short=BetaKlotho;AltName: Full=Klotho beta-like protein;
Polypeptide 1043 aa
For this sequence
Organism mouse
See UniProt | EBI for source
Annotated genes and markers Follow the symbol links to get more information on the GO terms, expression assays, orthologs, phenotypic alleles, and other information for the genes or markers below.
Type Symbol Name GO Terms Expression
Orthologs Phenotypic
Gene Klb klotho beta 11 3 8 17
Sequence references in MGI J:65636 Ito S, et al., Molecular cloning and expression analyses of mouse betaklotho, which encodes a novel klotho family protein. Mech Dev. 2000 Nov;98(1-2):115-9
J:100209 Ito S, et al., Impaired negative feedback suppression of bile acid synthesis in mice lacking betaKlotho. J Clin Invest. 2005 Aug 1;115(8):2202-2208
J:121336 Ogawa Y, et al., BetaKlotho is required for metabolic activity of fibroblast growth factor 21. Proc Natl Acad Sci U S A. 2007 May 1;104(18):7432-7

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
MGI 6.14
The Jackson Laboratory