Sequence Detail

ID/Version

Q99N32 Q99N31 B2RQN8 Q920J2 (UniProt | EBI)

Last sequence update: 2001-06-01
Last annotation update: 2024-01-24

Sequence description from provider

RecName: Full=Beta-klotho; Short=BKL; Short=BetaKlotho;AltName: Full=Klotho beta-like protein;

Provider

SWISS-PROT

Sequence

Polypeptide 1043 aa

Source

Organism mouse

See UniProt | EBI for source

Annotated genes and markers

Follow the symbol links to get more information on the GO terms, expression assays, orthologs, phenotypic alleles, and other information for the genes or markers below.

Type	Symbol	Name	GO Terms	Expression Assays	Orthologs	Phenotypic Alleles
Gene	Klb	klotho beta	18	101	3	22

Sequence references in MGI

J:65636 Ito S, et al., Molecular cloning and expression analyses of mouse betaklotho, which encodes a novel klotho family protein. Mech Dev. 2000 Nov;98(1-2):115-9
J:100209 Ito S, et al., Impaired negative feedback suppression of bile acid synthesis in mice lacking betaKlotho. J Clin Invest. 2005 Aug 1;115(8):2202-2208
J:121336 Ogawa Y, et al., BetaKlotho is required for metabolic activity of fibroblast growth factor 21. Proc Natl Acad Sci U S A. 2007 May 1;104(18):7432-7