Sequence Detail

ID/Version

Q99ML9 Q8CBC0 Q7TMR3 Q8C881 Q3UVL7 Q6NSW2 (UniProt | EBI)

Last sequence update: 2001-06-01
Last annotation update: 2025-02-05

Sequence description from provider

RecName: Full=E3 ubiquitin-protein ligase Arkadia {ECO:0000305|PubMed:11298452}; EC=2.3.2.27 {ECO:0000269|PubMed:23530056};AltName: Full=RING finger protein 111 {ECO:0000312|MGI:MGI:1934919};AltName: Full=RING-type E3 ubiquitin transferase Arkadia

Provider

SWISS-PROT

Sequence

Polypeptide 989 aa

Source

Organism mouse

See UniProt | EBI for source

Annotated genes and markers

Follow the symbol links to get more information on the GO terms, expression assays, orthologs, phenotypic alleles, and other information for the genes or markers below.

Type	Symbol	Name	GO Terms	Expression Assays	Orthologs	Phenotypic Alleles
Gene	Rnf111	ring finger 111	49	101	3	380

Sequence references in MGI

J:68833 Episkopou V, et al., Induction of the mammalian node requires Arkadia function in the extraembryonic lineages. Nature. 2001 Apr 12;410(6830):825-30
J:87112 Koinuma D, et al., Arkadia amplifies TGF-beta superfamily signalling through degradation of Smad7. EMBO J. 2003 Dec 15;22(24):6458-6470
J:99680 The FANTOM Consortium and RIKEN Genome Exploration Research Group and Genome Science Group (Genome Network Project Core Group), The Transcriptional Landscape of the Mammalian Genome. Science. 2005;309(5740):1559-1563
J:122005 Mavrakis KJ, et al., Arkadia Enhances Nodal/TGF-beta Signaling by Coupling Phospho-Smad2/3 Activity and Turnover. PLoS Biol. 2007 Mar 6;5(3):e67
J:204028 Erker Y, et al., Arkadia, a novel SUMO-targeted ubiquitin ligase involved in PML degradation. Mol Cell Biol. 2013 Jun;33(11):2163-77