Sequence Detail

ID/Version

Q8R502 Q8C296 Q8R0N7 Q8R3G5 Q3TEP9 (UniProt | EBI)

Last sequence update: 2002-06-01
Last annotation update: 2025-02-05

Sequence description from provider

RecName: Full=Volume-regulated anion channel subunit LRRC8C {ECO:0000303|PubMed:36522427, ECO:0000303|PubMed:36928458};AltName: Full=Factor for adipocyte differentiation 158 {ECO:0000303|PubMed:21804215};AltName: Full=Leucine-rich repeat-containing protei

Provider

SWISS-PROT

Sequence

Polypeptide 803 aa

Source

Organism mouse

See UniProt | EBI for source

Annotated genes and markers

Follow the symbol links to get more information on the GO terms, expression assays, orthologs, phenotypic alleles, and other information for the genes or markers below.

Type	Symbol	Name	GO Terms	Expression Assays	Orthologs	Phenotypic Alleles
Gene	Lrrc8c	leucine rich repeat containing 8 family, member C	45	97	3	9

Sequence references in MGI

J:92270 Tominaga K, et al., The novel gene fad158, having a transmembrane domain and leucine-rich repeat, stimulates adipocyte differentiation. J Biol Chem. 2004 Aug 13;279(33):34840-8
J:94212 Tominaga K, et al., Fad24, a mammalian homolog of Noc3p, is a positive regulator in adipocyte differentiation. J Cell Sci. 2004 Dec 1;117(Pt 25):6217-26
J:99680 The FANTOM Consortium and RIKEN Genome Exploration Research Group and Genome Science Group (Genome Network Project Core Group), The Transcriptional Landscape of the Mammalian Genome. Science. 2005;309(5740):1559-1563
J:247160 Hayashi T, et al., Factor for adipocyte differentiation 158 gene disruption prevents the body weight gain and insulin resistance induced by a high-fat diet. Biol Pharm Bull. 2011;34(8):1257-63
J:262352 Deneka D, et al., Structure of a volume-regulated anion channel of the LRRC8 family. Nature. 2018 May 16;
J:292518 Huttlin EL, et al., A tissue-specific atlas of mouse protein phosphorylation and expression. Cell. 2010 Dec 23;143(7):1174-89