Sequence Detail

ID/Version

Q8K1S2 B9EHC0 (UniProt | EBI)

Last sequence update: 2002-10-01
Last annotation update: 2025-02-05

Sequence description from provider

RecName: Full=Netrin receptor UNC5D;AltName: Full=Protein unc-5 homolog 4;AltName: Full=Protein unc-5 homolog D;Flags: Precursor;

Provider

SWISS-PROT

Sequence

Polypeptide 956 aa

Source

Organism mouse

See UniProt | EBI for source

Annotated genes and markers

Follow the symbol links to get more information on the GO terms, expression assays, orthologs, phenotypic alleles, and other information for the genes or markers below.

Type	Symbol	Name	GO Terms	Expression Assays	Orthologs	Phenotypic Alleles
Gene	Unc5d	unc-5 netrin receptor D	9	120	4	4

Sequence references in MGI

J:79319 Engelkamp D, Cloning of three mouse Unc5 genes and their expression patterns at mid-gestation. Mech Dev. 2002 Oct;118(1-2):191
J:141783 Sasaki S, et al., The cortical subventricular zone-specific molecule Svet1 is part of the nuclear RNA coded by the putative Netrin receptor gene Unc5d and is expressed in multipolar migrating cells. Mol Cell Neurosci. 2008 Aug;38(4):474-83
J:186020 Takemoto M, et al., Laminar and areal expression of unc5d and its role in cortical cell survival. Cereb Cortex. 2011 Aug;21(8):1925-34
J:196042 Yamagishi S, et al., FLRT2 and FLRT3 act as repulsive guidance cues for Unc5-positive neurons. EMBO J. 2011 Jul 20;30(14):2920-33
J:218226 Seiradake E, et al., FLRT structure: balancing repulsion and cell adhesion in cortical and vascular development. Neuron. 2014 Oct 22;84(2):370-85
J:224830 Lu YC, et al., Structural Basis of Latrophilin-FLRT-UNC5 Interaction in Cell Adhesion. Structure. 2015 Sep 1;23(9):1678-91