Sequence Detail

ID/Version

Q8K1A0 (UniProt | EBI)

Last sequence update: 2006-10-03
Last annotation update: 2025-02-05

Sequence description from provider

RecName: Full=rRNA N(6)-adenosine-methyltransferase METTL5 {ECO:0000305}; EC=2.1.1.- {ECO:0000269|PubMed:32783360};AltName: Full=Methyltransferase-like protein 5 {ECO:0000305};

Provider

SWISS-PROT

Sequence

Polypeptide 209 aa

Source

Organism mouse

See UniProt | EBI for source

Annotated genes and markers

Follow the symbol links to get more information on the GO terms, expression assays, orthologs, phenotypic alleles, and other information for the genes or markers below.

Type	Symbol	Name	GO Terms	Expression Assays	Orthologs	Phenotypic Alleles
Gene	Mettl5	methyltransferase 5, N6-adenosine	46	96	3	34

Sequence references in MGI

J:289086 Ignatova VV, et al., The rRNA m(6)A methyltransferase METTL5 is involved in pluripotency and developmental programs. Genes Dev. 2020 May 1;34(9-10):715-729
J:301381 Xing M, et al., The 18S rRNA m(6) A methyltransferase METTL5 promotes mouse embryonic stem cell differentiation. EMBO Rep. 2020 Oct 5;21(10):e49863
J:322368 Sepich-Poore C, et al., The METTL5-TRMT112 N(6)-methyladenosine methyltransferase complex regulates mRNA translation via 18S rRNA methylation. J Biol Chem. 2022 Jan 14;298(3):101590