Sequence Detail

ID/Version

Q8CIB5 Q8C542 Q8K035 (UniProt | EBI)

Last sequence update: 2003-03-01
Last annotation update: 2025-02-05

Sequence description from provider

RecName: Full=Fermitin family homolog 2;AltName: Full=Kindlin-2;AltName: Full=Pleckstrin homology domain-containing family C member 1;

Provider

SWISS-PROT

Sequence

Polypeptide 680 aa

Source

Organism mouse

See UniProt | EBI for source

Annotated genes and markers

Follow the symbol links to get more information on the GO terms, expression assays, orthologs, phenotypic alleles, and other information for the genes or markers below.

Type	Symbol	Name	GO Terms	Expression Assays	Orthologs	Phenotypic Alleles
Gene	Fermt2	fermitin family member 2	126	106	3	81

Sequence references in MGI

J:99680 The FANTOM Consortium and RIKEN Genome Exploration Research Group and Genome Science Group (Genome Network Project Core Group), The Transcriptional Landscape of the Mammalian Genome. Science. 2005;309(5740):1559-1563
J:134768 Montanez E, et al., Kindlin-2 controls bidirectional signaling of integrins. Genes Dev. 2008 May 15;22(10):1325-30
J:147662 Dowling JJ, et al., Kindlin-2 is an essential component of intercalated discs and is required for vertebrate cardiac structure and function. Circ Res. 2008 Feb 29;102(4):423-31
J:173278 Pluskota E, et al., The integrin coactivator kindlin-2 plays a critical role in angiogenesis in mice and zebrafish. Blood. 2011 May 5;117(18):4978-87
J:175678 Brunner M, et al., Osteoblast mineralization requires beta1 integrin/ICAP-1-dependent fibronectin deposition. J Cell Biol. 2011 Jul 25;194(2):307-22
J:292518 Huttlin EL, et al., A tissue-specific atlas of mouse protein phosphorylation and expression. Cell. 2010 Dec 23;143(7):1174-89