Sequence Detail

ID/Version

Q8BML1 F8WJF1 B1B545 F6ZD54 Q3UPU6 Q8CID1 Q9D5U9 Q14DP1 Q3TR48 Q5DU17 (UniProt | EBI)

Last sequence update: 2022-02-23
Last annotation update: 2025-02-05

Sequence description from provider

RecName: Full=[F-actin]-monooxygenase MICAL2 {ECO:0000305}; EC=1.14.13.225 {ECO:0000269|PubMed:23911929, ECO:0000269|PubMed:23927065};AltName: Full=ERK2-binding testicular protein 1 {ECO:0000303|PubMed:18241670};AltName: Full=MICAL C-terminal-like

Provider

SWISS-PROT

Sequence

Polypeptide 1951 aa

Source

Organism mouse

See UniProt | EBI for source

Annotated genes and markers

Follow the symbol links to get more information on the GO terms, expression assays, orthologs, phenotypic alleles, and other information for the genes or markers below.

Type	Symbol	Name	GO Terms	Expression Assays	Orthologs	Phenotypic Alleles
Gene	Mical2	microtubule associated monooxygenase, calponin and LIM domain containing 2	47	99	4	5

Sequence references in MGI

J:99680 The FANTOM Consortium and RIKEN Genome Exploration Research Group and Genome Science Group (Genome Network Project Core Group), The Transcriptional Landscape of the Mammalian Genome. Science. 2005;309(5740):1559-1563
J:136810 Miura K, et al., Molecular cloning of Ebitein1: a novel extracellular signal-regulated kinase 2-binding protein in testis. Biochem Biophys Res Commun. 2008 Apr 4;368(2):336-42
J:140064 Miura K, et al., Identification of ERK2-binding domain of EBITEIN1, a novel ERK2-binding protein. Biochim Biophys Acta. 2008 Sep;1784(9):1319-25
J:201326 Lee BC, et al., MsrB1 and MICALs regulate actin assembly and macrophage function via reversible stereoselective methionine oxidation. Mol Cell. 2013 Aug 8;51(3):397-404
J:245335 McDonald CA, et al., Actin stimulates reduction of the MICAL-2 monooxygenase domain. Biochemistry. 2013 Sep 03;52(35):6076-84
J:292518 Huttlin EL, et al., A tissue-specific atlas of mouse protein phosphorylation and expression. Cell. 2010 Dec 23;143(7):1174-89