Sequence Detail

ID/Version

Q7TNF0 (UniProt | EBI)

Last sequence update: 2003-10-01
Last annotation update: 2025-06-18

Sequence description from provider

RecName: Full=Double C2-like domain-containing protein alpha; Short=Doc2-alpha;

Provider

SWISS-PROT

Sequence

Polypeptide 405 aa

Source

Organism mouse

See UniProt | EBI for source

Annotated genes and markers

Follow the symbol links to get more information on the GO terms, expression assays, orthologs, phenotypic alleles, and other information for the genes or markers below.

Type	Symbol	Name	GO Terms	Expression Assays	Orthologs	Phenotypic Alleles
Gene	Doc2a	double C2, alpha	33	97	3	11

Sequence references in MGI

J:133380 Higashio H, et al., Doc2{alpha} and Munc13-4 Regulate Ca2+-Dependent Secretory Lysosome Exocytosis in Mast Cells. J Immunol. 2008 Apr 1;180(7):4774-84
J:158605 Groffen AJ, et al., Doc2b is a high-affinity Ca2+ sensor for spontaneous neurotransmitter release. Science. 2010 Mar 26;327(5973):1614-8