Sequence Detail

ID/Version

Q7TMI3 Q8K1I5 Q8BY30 Q8BJP6 Q8BG56 (UniProt | EBI)

Last sequence update: 2003-10-01
Last annotation update: 2024-03-27

Sequence description from provider

RecName: Full=E3 ubiquitin-protein ligase UHRF2; EC=2.3.2.27;AltName: Full=NIRF;AltName: Full=Np95-like ring finger protein;AltName: Full=Nuclear protein 97;AltName: Full=Nuclear zinc finger protein Np97;AltName: Full=RING-type E3 ubiquitin transf

Provider

SWISS-PROT

Sequence

Polypeptide 803 aa

Source

Organism mouse

See UniProt | EBI for source

Annotated genes and markers

Follow the symbol links to get more information on the GO terms, expression assays, orthologs, phenotypic alleles, and other information for the genes or markers below.

Type	Symbol	Name	GO Terms	Expression Assays	Orthologs	Phenotypic Alleles
Gene	Uhrf2	ubiquitin-like, containing PHD and RING finger domains 2	28	104	2	16

Sequence references in MGI

J:99680 The FANTOM Consortium and RIKEN Genome Exploration Research Group and Genome Science Group (Genome Network Project Core Group), The Transcriptional Landscape of the Mammalian Genome. Science. 2005;309(5740):1559-1563
J:183195 Pichler G, et al., Cooperative DNA and histone binding by Uhrf2 links the two major repressive epigenetic pathways. J Cell Biochem. 2011 Sep;112(9):2585-93
J:241384 Chen R, et al., The 5-Hydroxymethylcytosine (5hmC) Reader UHRF2 Is Required for Normal Levels of 5hmC in Mouse Adult Brain and Spatial Learning and Memory. J Biol Chem. 2017 Mar 17;292(11):4533-4543
J:262684 Liu Y, et al., UHRF2 regulates local 5-methylcytosine and suppresses spontaneous seizures. Epigenetics. 2017 Jul 3;12(7):551-560
J:292518 Huttlin EL, et al., A tissue-specific atlas of mouse protein phosphorylation and expression. Cell. 2010 Dec 23;143(7):1174-89