Sequence Detail

ID/Version

Q7M6Z0 A2RTJ0 Q3UQ62 (UniProt | EBI)

Last sequence update: 2003-12-15
Last annotation update: 2025-02-05

Sequence description from provider

RecName: Full=Reticulon-4 receptor-like 2;AltName: Full=Nogo receptor-like 3;AltName: Full=Nogo-66 receptor homolog 1;AltName: Full=Nogo-66 receptor-related protein 2; Short=NgR2 {ECO:0000303|PubMed:19367338};Flags: Precursor;

Provider

SWISS-PROT

Sequence

Polypeptide 420 aa

Source

Organism mouse

See UniProt | EBI for source

Annotated genes and markers

Follow the symbol links to get more information on the GO terms, expression assays, orthologs, phenotypic alleles, and other information for the genes or markers below.

Type	Symbol	Name	GO Terms	Expression Assays	Orthologs	Phenotypic Alleles
Gene	Rtn4rl2	reticulon 4 receptor-like 2	41	102	4	12

Sequence references in MGI

J:84277 Barton WA, et al., Structure and axon outgrowth inhibitor binding of the Nogo-66 receptor and related proteins. EMBO J. 2003 Jul 1;22(13):3291-302
J:86943 Lauren J, et al., Two novel mammalian Nogo receptor homologs differentially expressed in the central and peripheral nervous systems. Mol Cell Neurosci. 2003 Nov;24(3):581-94
J:99680 The FANTOM Consortium and RIKEN Genome Exploration Research Group and Genome Science Group (Genome Network Project Core Group), The Transcriptional Landscape of the Mammalian Genome. Science. 2005;309(5740):1559-1563
J:182292 Wills ZP, et al., The nogo receptor family restricts synapse number in the developing hippocampus. Neuron. 2012 Feb 9;73(3):466-81
J:191258 Dickendesher TL, et al., NgR1 and NgR3 are receptors for chondroitin sulfate proteoglycans. Nat Neurosci. 2012 May;15(5):703-12
J:223638 Worter V, et al., Inhibitory activity of myelin-associated glycoprotein on sensory neurons is largely independent of NgR1 and NgR2 and resides within Ig-Like domains 4 and 5. PLoS One. 2009;4(4):e5218
J:238442 Palandri A, et al., Myelin-associated glycoprotein modulates apoptosis of motoneurons during early postnatal development via NgR/p75(NTR) receptor-mediated activation of RhoA signaling pathways. Cell Death Dis. 2015 Sep 03;6:e1876
J:238817 Yoo SW, et al., Agenesis of the corpus callosum in Nogo receptor deficient mice. J Comp Neurol. 2017 Feb 01;525(2):291-301