Sequence Detail

ID/Version

Q6PHU5 Q3UHE2 Q9QXW6 A2AEE8 Q8K043 (UniProt | EBI)

Last sequence update: 2004-07-05
Last annotation update: 2024-03-27

Sequence description from provider

RecName: Full=Sortilin {ECO:0000305};AltName: Full=Neurotensin receptor 3; Short=NTR3; Short=mNTR3;Flags: Precursor;

Provider

SWISS-PROT

Sequence

Polypeptide 825 aa

Source

Organism mouse

See UniProt | EBI for source

Annotated genes and markers

Follow the symbol links to get more information on the GO terms, expression assays, orthologs, phenotypic alleles, and other information for the genes or markers below.

Type	Symbol	Name	GO Terms	Expression Assays	Orthologs	Phenotypic Alleles
Gene	Sort1	sortilin 1	90	103	4	18

Sequence references in MGI

J:45627 Morris NJ, et al., Sortilin is the major 110-kDa protein in GLUT4 vesicles from adipocytes. J Biol Chem. 1998 Feb 6;273(6):3582-7
J:53414 Hermans-Borgmeyer I, et al., Expression of the 100-kDa neurotensin receptor sortilin during mouse embryonal development. Brain Res Mol Brain Res. 1999 Mar 5;65(2):216-9
J:69031 Navarro V, et al., Pharmacological properties of the mouse neurotensin receptor 3. Maintenance of cell surface receptor during internalization of neurotensin. FEBS Lett. 2001 Apr 20;495(1-2):100-5
J:99400 Shi J, et al., Sortilin Is Essential and Sufficient for the Formation of Glut4 Storage Vesicles in 3T3-L1 Adipocytes. Dev Cell. 2005 Jul;9(1):99-108
J:99680 The FANTOM Consortium and RIKEN Genome Exploration Research Group and Genome Science Group (Genome Network Project Core Group), The Transcriptional Landscape of the Mammalian Genome. Science. 2005;309(5740):1559-1563
J:149884 Kim T, et al., NRH2 is a trafficking switch to regulate sortilin localization and permit proneurotrophin-induced cell death. EMBO J. 2009 Jun 3;28(11):1612-23
J:170255 Vaegter CB, et al., Sortilin associates with Trk receptors to enhance anterograde transport and neurotrophin signaling. Nat Neurosci. 2011 Jan;14(1):54-61
J:292518 Huttlin EL, et al., A tissue-specific atlas of mouse protein phosphorylation and expression. Cell. 2010 Dec 23;143(7):1174-89