Sequence Detail

ID/Version

Q64669 (UniProt | EBI)

Last sequence update: 2007-01-23
Last annotation update: 2024-03-27

Sequence description from provider

RecName: Full=NAD(P)H dehydrogenase [quinone] 1; EC=1.6.5.2 {ECO:0000269|PubMed:8999809};AltName: Full=Azoreductase;AltName: Full=DT-diaphorase {ECO:0000303|PubMed:8999809}; Short=DTD;AltName: Full=Menadione reductase;AltName: Full=NAD(P)H

Provider

SWISS-PROT

Sequence

Polypeptide 274 aa

Source

Organism mouse

See UniProt | EBI for source

Annotated genes and markers

Follow the symbol links to get more information on the GO terms, expression assays, orthologs, phenotypic alleles, and other information for the genes or markers below.

Type	Symbol	Name	GO Terms	Expression Assays	Orthologs	Phenotypic Alleles
Gene	Nqo1	NAD(P)H dehydrogenase, quinone 1	61	104	3	21

Sequence references in MGI

J:20481 Chen S, et al., Mouse liver NAD(P)H:quinone acceptor oxidoreductase: protein sequence analysis by tandem mass spectrometry, cDNA cloning, expression in Escherichia coli, and enzyme activity analysis. Protein Sci. 1994 Aug;3(8):1296-304
J:22587 Vasiliou V, et al., Mouse dioxin-inducible NAD(P)H: menadione oxidoreductase: NMO1 cDNA sequence and genetic differences in mRNA levels. Pharmacogenetics. 1994 Dec;4(6):341-8
J:38455 Chen S, et al., Molecular basis of the catalytic differences among DT-diaphorase of human, rat, and mouse. J Biol Chem. 1997 Jan 17;272(3):1437-9
J:61376 Faig M, et al., Structures of recombinant human and mouse NAD(P)H:quinone oxidoreductases: species comparison and structural changes with substrate binding and release. Proc Natl Acad Sci U S A. 2000 Mar 28;97(7):3177-82
J:292518 Huttlin EL, et al., A tissue-specific atlas of mouse protein phosphorylation and expression. Cell. 2010 Dec 23;143(7):1174-89