Sequence Detail

ID/Version

Q63955 A6H6N6 (UniProt | EBI)

Last sequence update: 2011-07-27
Last annotation update: 2024-01-24

Sequence description from provider

RecName: Full=POU domain, class 4, transcription factor 3 {ECO:0000312|MGI:MGI:102523};AltName: Full=Brain-specific homeobox/POU domain protein 3C; Short=Brain-3C; Short=Brn-3C;AltName: Full=Brn-3.1 {ECO:0000303|PubMed:8637595};

Provider

SWISS-PROT

Sequence

Polypeptide 338 aa

Source

Organism mouse

See UniProt | EBI for source

Annotated genes and markers

Follow the symbol links to get more information on the GO terms, expression assays, orthologs, phenotypic alleles, and other information for the genes or markers below.

Type	Symbol	Name	GO Terms	Expression Assays	Orthologs	Phenotypic Alleles
Gene	Pou4f3	POU domain, class 4, transcription factor 3	35	125	3	15

Sequence references in MGI

J:16381 Theil T, et al., Mouse Brn-3 family of POU transcription factors: a new aminoterminal domain is crucial for the oncogenic activity of Brn-3a. Nucleic Acids Res. 1993 Dec 25;21(25):5921-9
J:18174 Theil T, et al., Chromosomal localization and sequences of the murine Brn-3 family of developmental control genes. Cytogenet Cell Genet. 1994;66(4):267-71
J:33502 Erkman L, et al., Role of transcription factors Brn-3.1 and Brn-3.2 in auditory and visual system development. Nature. 1996 Jun 13;381(6583):603-6
J:34809 Gerrero MR, et al., Brn-3.0: a POU-domain protein expressed in the sensory, immune, and endocrine systems that functions on elements distinct from known octamer motifs. Proc Natl Acad Sci U S A. 1993 Nov 15;90(22):10841-5
J:183949 Zou M, et al., Brn3a/Pou4f1 regulates dorsal root ganglion sensory neuron specification and axonal projection into the spinal cord. Dev Biol. 2012 Apr 15;364(2):114-27
J:239195 Li R, et al., Isl1 and Pou4f2 form a complex to regulate target genes in developing retinal ganglion cells. PLoS One. 2014;9(3):e92105
J:239217 Morris PJ, et al., The opposite and antagonistic effects of the closely related POU family transcription factors Brn-3a and Brn-3b on the activity of a target promoter are dependent on differences in the POU domain. Mol Cell Biol. 1994 Oct;14(10):6907-14