Sequence Detail

ID/Version

Q61144 O54977 Q91VS3 Q9D616 P97934 P97935 (UniProt | EBI)

Last sequence update: 2003-09-26
Last annotation update: 2025-02-05

Sequence description from provider

RecName: Full=Presenilin-2; Short=PS-2; EC=3.4.23.-;Contains: RecName: Full=Presenilin-2 NTF subunit;Contains: RecName: Full=Presenilin-2 CTF subunit;

Provider

SWISS-PROT

Sequence

Polypeptide 448 aa

Source

Organism mouse

See UniProt | EBI for source

Annotated genes and markers

Follow the symbol links to get more information on the GO terms, expression assays, orthologs, phenotypic alleles, and other information for the genes or markers below.

Type	Symbol	Name	GO Terms	Expression Assays	Orthologs	Phenotypic Alleles
Gene	Psen2	presenilin 2	130	102	3	16

Sequence references in MGI

J:33763 Vito P, et al., Interfering with apoptosis: Ca(2+)-binding protein ALG-2 and Alzheimer's disease gene ALG-3. Science. 1996 Jan 26;271(5248):521-5
J:37098 Vito P, et al., Requirement of the familial Alzheimer's disease gene PS2 for apoptosis. Opposing effect of ALG-3. J Biol Chem. 1996 Dec 6;271(49):31025-8
J:99680 The FANTOM Consortium and RIKEN Genome Exploration Research Group and Genome Science Group (Genome Network Project Core Group), The Transcriptional Landscape of the Mammalian Genome. Science. 2005;309(5740):1559-1563
J:143718 Trost M, et al., The phagosomal proteome in interferon-gamma-activated macrophages. Immunity. 2009 Jan;30(1):143-54
J:292518 Huttlin EL, et al., A tissue-specific atlas of mouse protein phosphorylation and expression. Cell. 2010 Dec 23;143(7):1174-89