Sequence Detail

ID/Version

Q60994 Q6GTX4 Q62400 Q9DC68 (UniProt | EBI)

Last sequence update: 2012-10-03
Last annotation update: 2024-03-27

Sequence description from provider

RecName: Full=Adiponectin;AltName: Full=30 kDa adipocyte complement-related protein;AltName: Full=Adipocyte complement-related 30 kDa protein; Short=ACRP30;AltName: Full=Adipocyte, C1q and collagen domain-containing protein;AltName: Full=Adipocyte

Provider

SWISS-PROT

Sequence

Polypeptide 247 aa

Source

Organism mouse

See UniProt | EBI for source

Annotated genes and markers

Follow the symbol links to get more information on the GO terms, expression assays, orthologs, phenotypic alleles, and other information for the genes or markers below.

Type	Symbol	Name	GO Terms	Expression Assays	Orthologs	Phenotypic Alleles
Gene	Adipoq	adiponectin, C1Q and collagen domain containing	142	114	4	27

Sequence references in MGI

J:32911 Hu E, et al., AdipoQ is a novel adipose-specific gene dysregulated in obesity. J Biol Chem. 1996 May 3;271(18):10697-703
J:32963 Scherer PE, et al., A novel serum protein similar to C1q, produced exclusively in adipocytes. J Biol Chem. 1995 Nov 10;270(45):26746-9
J:63965 Das K, et al., Chromosomal localization, expression pattern, and promoter analysis of the mouse gene encoding adipocyte-specific secretory protein Acrp30. Biochem Biophys Res Commun. 2001 Feb 2;280(4):1120-9
J:70692 Yamauchi T, et al., The fat-derived hormone adiponectin reverses insulin resistance associated with both lipoatrophy and obesity. Nat Med. 2001 Aug;7(8):941-6
J:70712 Sato C, et al., Identification and Adipocyte Differentiation-dependent Expression of the Unique Disialic Acid Residue in an Adipose Tissue-specific Glycoprotein, Adipo Q. J Biol Chem. 2001 Aug 3;276(31):28849-56
J:93108 Berg AH, et al., The adipocyte-secreted protein Acrp30 enhances hepatic insulin action. Nat Med. 2001 Aug;7(8):947-53
J:99086 Wang Y, et al., Adiponectin inhibits cell proliferation by interacting with several growth factors in an oligomerization-dependent manner. J Biol Chem. 2005 May 6;280(18):18341-7
J:99680 The FANTOM Consortium and RIKEN Genome Exploration Research Group and Genome Science Group (Genome Network Project Core Group), The Transcriptional Landscape of the Mammalian Genome. Science. 2005;309(5740):1559-1563
J:113740 Wang Y, et al., Post-translational modifications of the four conserved lysine residues within the collagenous domain of adiponectin are required for the formation of its high molecular weight oligomeric complex. J Biol Chem. 2006 Jun 16;281(24):16391-400
J:146036 Wong GW, et al., Identification and characterization of CTRP9, a novel secreted glycoprotein, from adipose tissue that reduces serum glucose in mice and forms heterotrimers with adiponectin. FASEB J. 2009 Jan;23(1):241-58
J:195451 Ruotsalainen H, et al., The activities of lysyl hydroxylase 3 (LH3) regulate the amount and oligomerization status of adiponectin. PLoS One. 2012;7(11):e50045
J:292518 Huttlin EL, et al., A tissue-specific atlas of mouse protein phosphorylation and expression. Cell. 2010 Dec 23;143(7):1174-89