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Sequence Detail
Q5FW52 Q9D6X9 (UniProt | EBI) Last sequence update: 2005-03-01
Last annotation update: 2021-02-10
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RecName: Full=Muscular LMNA-interacting protein {ECO:0000312|MGI:MGI:1916892};AltName: Full=Cardiac Isl1-interacting protein {ECO:0000303|PubMed:22343712}; Short=CIP {ECO:0000303|PubMed:22343712};AltName: Full=Muscular-enriched A-type laminin-inte
Polypeptide 269 aa
For this sequence
Organism mouse
See UniProt | EBI for source
Annotated genes and markers Follow the symbol links to get more information on the GO terms, expression assays, orthologs, phenotypic alleles, and other information for the genes or markers below.
Type Symbol Name GO Terms Expression
Orthologs Phenotypic
Gene Mlip muscular LMNA-interacting protein 18 70 6 11
Sequence references in MGI J:99680 The FANTOM Consortium and RIKEN Genome Exploration Research Group and Genome Science Group (Genome Network Project Core Group), The Transcriptional Landscape of the Mammalian Genome. Science. 2005;309(5740):1559-1563
J:173222 Ahmady E, et al., Identification of a Novel Muscle A-type Lamin-interacting Protein (MLIP). J Biol Chem. 2011 Jun 3;286(22):19702-13
J:212665 Huang ZP, et al., CIP, a cardiac Isl1-interacting protein, represses cardiomyocyte hypertrophy. Circ Res. 2012 Mar 16;110(6):818-30
J:227485 Huang ZP, et al., Cardiomyocyte-enriched protein CIP protects against pathophysiological stresses and regulates cardiac homeostasis. J Clin Invest. 2015 Nov 2;125(11):4122-34
J:243471 Cattin ME, et al., Deletion of MLIP (muscle-enriched A-type lamin-interacting protein) leads to cardiac hyperactivation of Akt/mammalian target of rapamycin (mTOR) and impaired cardiac adaptation. J Biol Chem. 2015 Oct 30;290(44):26699-714
J:292518 Huttlin EL, et al., A tissue-specific atlas of mouse protein phosphorylation and expression. Cell. 2010 Dec 23;143(7):1174-89

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
MGI 6.16
The Jackson Laboratory