Sequence Detail

ID/Version

Q31125 Q3TVU6 Q9Z1W1 (UniProt | EBI)

Last sequence update: 2001-01-24
Last annotation update: 2024-01-24

Sequence description from provider

RecName: Full=Zinc transporter SLC39A7;AltName: Full=Histidine-rich membrane protein Ke4;AltName: Full=Solute carrier family 39 member 7;AltName: Full=Zrt-, Irt-like protein 7 {ECO:0000303|PubMed:15705588}; Short=ZIP7 {ECO:0000303|PubMed:15705588}

Provider

SWISS-PROT

Sequence

Polypeptide 476 aa

Source

Organism mouse

See UniProt | EBI for source

Annotated genes and markers

Follow the symbol links to get more information on the GO terms, expression assays, orthologs, phenotypic alleles, and other information for the genes or markers below.

Type	Symbol	Name	GO Terms	Expression Assays	Orthologs	Phenotypic Alleles
Gene	Slc39a7	solute carrier family 39 (zinc transporter), member 7	22	100	3	7

Sequence references in MGI

J:10170 St.-Jacques B, et al., A putative transmembrane protein with histidine-rich charge clusters encoded in the H-2K/tw5 region of mice. Mol Cell Biol. 1990 Jan;10(1):138-45
J:98700 Huang L, et al., The ZIP7 gene (Slc39a7) encodes a zinc transporter involved in zinc homeostasis of the Golgi apparatus. J Biol Chem. 2005 Apr 15;280(15):15456-63
J:99680 The FANTOM Consortium and RIKEN Genome Exploration Research Group and Genome Science Group (Genome Network Project Core Group), The Transcriptional Landscape of the Mammalian Genome. Science. 2005;309(5740):1559-1563
J:236234 Ohashi W, et al., Zinc Transporter SLC39A7/ZIP7 Promotes Intestinal Epithelial Self-Renewal by Resolving ER Stress. PLoS Genet. 2016 Oct;12(10):e1006349
J:244716 Bin BH, et al., Requirement of Zinc Transporter SLC39A7/ZIP7 for Dermal Development to Fine-Tune Endoplasmic Reticulum Function by Regulating Protein Disulfide Isomerase. J Invest Dermatol. 2017 Aug;137(8):1682-1691
J:282388 Anzilotti C, et al., An essential role for the Zn(2+) transporter ZIP7 in B cell development. Nat Immunol. 2019 Mar;20(3):350-361
J:292518 Huttlin EL, et al., A tissue-specific atlas of mouse protein phosphorylation and expression. Cell. 2010 Dec 23;143(7):1174-89
J:334001 Lv M, et al., METTL9 mediated N1-histidine methylation of zinc transporters is required for tumor growth. Protein Cell. 2021 Dec;12(12):965-970