Sequence Detail

ID/Version

Q2TV84 O70334 Q3TPG5 Q2WEA6 Q640P5 Q5U4B3 Q3UFV6 Q3UG69 Q3UEW7 Q3UFW1 (UniProt | EBI)

Last sequence update: 2008-04-08
Last annotation update: 2024-01-24

Sequence description from provider

RecName: Full=Transient receptor potential cation channel subfamily M member 1;AltName: Full=Long transient receptor potential channel 1; Short=LTrpC1;AltName: Full=Melastatin-1;

Provider

SWISS-PROT

Sequence

Polypeptide 1622 aa

Source

Organism mouse

See UniProt | EBI for source

Annotated genes and markers

Follow the symbol links to get more information on the GO terms, expression assays, orthologs, phenotypic alleles, and other information for the genes or markers below.

Type	Symbol	Name	GO Terms	Expression Assays	Orthologs	Phenotypic Alleles
Gene	Trpm1	transient receptor potential cation channel, subfamily M, member 1	24	107	4	15

Sequence references in MGI

J:47077 Duncan LM, et al., Down-regulation of the novel gene melastatin correlates with potential for melanoma metastasis. Cancer Res. 1998 Apr 1;58(7):1515-20
J:99680 The FANTOM Consortium and RIKEN Genome Exploration Research Group and Genome Science Group (Genome Network Project Core Group), The Transcriptional Landscape of the Mammalian Genome. Science. 2005;309(5740):1559-1563
J:154776 Morgans CW, et al., TRPM1 is required for the depolarizing light response in retinal ON-bipolar cells. Proc Natl Acad Sci U S A. 2009 Nov 10;106(45):19174-8
J:156502 Koike C, et al., TRPM1 is a component of the retinal ON bipolar cell transduction channel in the mGluR6 cascade. Proc Natl Acad Sci U S A. 2010 Jan 5;107(1):332-7
J:211063 Ray TA, et al., GPR179 is required for high sensitivity of the mGluR6 signaling cascade in depolarizing bipolar cells. J Neurosci. 2014 Apr 30;34(18):6334-43
J:214871 Orlandi C, et al., Orphan receptor GPR179 forms macromolecular complexes with components of metabotropic signaling cascade in retina ON-bipolar neurons. Invest Ophthalmol Vis Sci. 2013;54(10):7153-61
J:266887 Agosto MA, et al., A Large Endoplasmic Reticulum-Resident Pool of TRPM1 in Retinal ON-Bipolar Cells. eNeuro. 2018 May-Jun;5(3):ENEURO.0143-18.2018