Sequence Detail

ID/Version

Q08048 Q6LBE6 Q61662 O55027 Q53WS5 Q64007 (UniProt | EBI)

Last sequence update: 1995-11-01
Last annotation update: 2025-02-05

Sequence description from provider

RecName: Full=Hepatocyte growth factor;AltName: Full=Hepatopoietin-A;AltName: Full=Scatter factor; Short=SF;Contains: RecName: Full=Hepatocyte growth factor alpha chain;Contains: RecName: Full=Hepatocyte growth factor beta chain;Flags: Precursor

Provider

SWISS-PROT

Sequence

Polypeptide 728 aa

Source

Organism mouse

See UniProt | EBI for source

Annotated genes and markers

Follow the symbol links to get more information on the GO terms, expression assays, orthologs, phenotypic alleles, and other information for the genes or markers below.

Type	Symbol	Name	GO Terms	Expression Assays	Orthologs	Phenotypic Alleles
Gene	Hgf	hepatocyte growth factor	55	162	4	25

Sequence references in MGI

J:15708 Liu Y, et al., Molecular cloning and characterization of cDNA encoding mouse hepatocyte growth factor. Biochim Biophys Acta. 1993 Nov 16;1216(2):299-303
J:17199 Sasaki M, et al., Identification of mouse mammary fibroblast-derived mammary growth factor as hepatocyte growth factor. Biochem Biophys Res Commun. 1994 Mar 15;199(2):772-9
J:19405 Lee CC, et al., Structure, genetic mapping, and expression of the mouse Hgf/scatter factor gene. Cell Adhes Commun. 1993 Sep;1(2):101-11
J:22292 Plaschke-Schlutter A, et al., Characterization of the scatter factor/hepatocyte growth factor gene promoter. Positive and negative regulatory elements direct gene expression to mesenchymal cells. J Biol Chem. 1995 Jan 13;270(2):830-6
J:45939 Jakubczak JL, et al., NK1, a natural splice variant of hepatocyte growth factor/scatter factor, is a partial agonist in vivo. Mol Cell Biol. 1998 Mar;18(3):1275-83
J:162562 Tolbert WD, et al., Structural basis for agonism and antagonism of hepatocyte growth factor. Proc Natl Acad Sci U S A. 2010 Jul 27;107(30):13264-9
J:248279 Tolbert WD, et al., A mechanistic basis for converting a receptor tyrosine kinase agonist to an antagonist. Proc Natl Acad Sci U S A. 2007 Sep 11;104(37):14592-7