Sequence Detail

ID/Version

P97820 (UniProt | EBI)

Last sequence update: 1997-05-01
Last annotation update: 2025-02-05

Sequence description from provider

RecName: Full=Mitogen-activated protein kinase kinase kinase kinase 4; EC=2.7.11.1;AltName: Full=HPK/GCK-like kinase HGK;AltName: Full=MAPK/ERK kinase kinase kinase 4; Short=MEK kinase kinase 4; Short=MEKKK 4;AltName: Full=Nck-inte

Provider

SWISS-PROT

Sequence

Polypeptide 1233 aa

Source

Organism mouse

See UniProt | EBI for source

Annotated genes and markers

Follow the symbol links to get more information on the GO terms, expression assays, orthologs, phenotypic alleles, and other information for the genes or markers below.

Type	Symbol	Name	GO Terms	Expression Assays	Orthologs	Phenotypic Alleles
Gene	Map4k4	mitogen-activated protein kinase kinase kinase kinase 4	48	101	3	50

Sequence references in MGI

J:39300 Su YC, et al., NIK is a new Ste20-related kinase that binds NCK and MEKK1 and activates the SAPK/JNK cascade via a conserved regulatory domain. EMBO J. 1997 Mar 17;16(6):1279-90
J:292518 Huttlin EL, et al., A tissue-specific atlas of mouse protein phosphorylation and expression. Cell. 2010 Dec 23;143(7):1174-89