About   Help   FAQ
Sequence Detail
ID/Version
P56546 O54855 O88462 (UniProt | EBI) Last sequence update: 2000-12-01
Last annotation update: 2025-02-05
Sequence
description
from provider
RecName: Full=C-terminal-binding protein 2; Short=CtBP2;
Provider SWISS-PROT
Sequence
Polypeptide 445 aa
For this sequence
Source
Organism mouse
See UniProt | EBI for source
Annotated genes and markers Follow the symbol links to get more information on the GO terms, expression assays, orthologs, phenotypic alleles, and other information for the genes or markers below.
Type Symbol Name GO Terms Expression
Assays
Orthologs Phenotypic
Alleles
Gene Ctbp2 C-terminal binding protein 2 66 120 3 20
Sequence references in MGI J:45956 Katsanis N, et al., A novel C-terminal binding protein (CTBP2) is closely related to CTBP1, an adenovirus E1A-binding protein, and maps to human chromosome 21q21.3. Genomics. 1998 Jan 15;47(2):294-9
J:49837 Turner J, et al., Cloning and characterization of mCtBP2, a co-repressor that associates with basic Kruppel-like factor and other mammalian transcriptional regulators. EMBO J. 1998 Sep 1;17(17):5129-40
J:58553 Furusawa T, et al., Identification of CtBP1 and CtBP2 as corepressors of zinc finger-homeodomain factor deltaEF1. Mol Cell Biol. 1999 Dec;19(12):8581-90
J:114142 Christian M, et al., Characterization of four autonomous repression domains in the corepressor receptor interacting protein 140. J Biol Chem. 2004 Apr 9;279(15):15645-51
J:114657 Quinlan KG, et al., Specific recognition of ZNF217 and other zinc finger proteins at a surface groove of C-terminal binding proteins. Mol Cell Biol. 2006 Nov;26(21):8159-72
J:114884 Ueda J, et al., Zinc finger protein Wiz links G9a/GLP histone methyltransferases to the co-repressor molecule CtBP. J Biol Chem. 2006 Jul 21;281(29):20120-8
J:153416 Kajimura S, et al., Regulation of the brown and white fat gene programs through a PRDM16/CtBP transcriptional complex. Genes Dev. 2008 May 15;22(10):1397-409
J:292518 Huttlin EL, et al., A tissue-specific atlas of mouse protein phosphorylation and expression. Cell. 2010 Dec 23;143(7):1174-89
J:306378 Guo A, et al., Immunoaffinity enrichment and mass spectrometry analysis of protein methylation. Mol Cell Proteomics. 2014 Jan;13(1):372-87

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support.
last database update
03/25/2025
MGI 6.24
The Jackson Laboratory