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Sequence Detail
P54310 Q6GU16 P97866 Q8CDI9 Q3TE34 (UniProt | EBI) Last sequence update: 2006-01-24
Last annotation update: 2019-05-08
from provider
RecName: Full=Hormone-sensitive lipase; Short=HSL; EC=;
Polypeptide 759 aa
For this sequence
Organism mouse
See UniProt | EBI for source
Annotated genes and markers Follow the symbol links to get more information on the GO terms, expression assays, orthologs, phenotypic alleles, and other information for the genes or markers below.
Type Symbol Name GO Terms Expression
Orthologs Phenotypic
Gene Lipe lipase, hormone sensitive 35 0 7 11
Sequence references in MGI J:21904 Li Z, et al., Isolation and characterization of the gene for mouse hormone-sensitive lipase. Genomics. 1994 Nov 15;24(2):259-65
J:38915 Sztrolovics R, et al., Hormone-sensitive lipase (Lipe): sequence analysis of the 129Sv mouse Lipe gene. Mamm Genome. 1997 Feb;8(2):86-9
J:99680 The FANTOM Consortium and RIKEN Genome Exploration Research Group and Genome Science Group (Genome Network Project Core Group), The Transcriptional Landscape of the Mammalian Genome. Science. 2005;309(5740):1559-1563
J:175186 Daval M, et al., Anti-lipolytic action of AMP-activated protein kinase in rodent adipocytes. J Biol Chem. 2005 Jul 1;280(26):25250-7
J:194928 Liew CW, et al., Ablation of TRIP-Br2, a regulator of fat lipolysis, thermogenesis and oxidative metabolism, prevents diet-induced obesity and insulin resistance. Nat Med. 2013 Feb;19(2):217-26
J:207819 Wang H, et al., Activation of hormone-sensitive lipase requires two steps, protein phosphorylation and binding to the PAT-1 domain of lipid droplet coat proteins. J Biol Chem. 2009 Nov 13;284(46):32116-25

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
MGI 6.14
The Jackson Laboratory