Sequence Detail

ID/Version

P51881 Q61311 (UniProt | EBI)

Last sequence update: 2007-01-23
Last annotation update: 2025-02-05

Sequence description from provider

RecName: Full=ADP/ATP translocase 2 {ECO:0000305};AltName: Full=ADP,ATP carrier protein 2 {ECO:0000303|PubMed:31341297};AltName: Full=Adenine nucleotide translocator 2 {ECO:0000303|PubMed:10974536, ECO:0000303|PubMed:8903724}; Short=ANT 2 {ECO:000

Provider

SWISS-PROT

Sequence

Polypeptide 298 aa

Source

Organism mouse

See UniProt | EBI for source

Annotated genes and markers

Follow the symbol links to get more information on the GO terms, expression assays, orthologs, phenotypic alleles, and other information for the genes or markers below.

Type	Symbol	Name	GO Terms	Expression Assays	Orthologs	Phenotypic Alleles
Gene	Slc25a5	solute carrier family 25 (mitochondrial carrier, adenine nucleotide translocator), member 5	58	102	4	13

Sequence references in MGI

J:30840 Ellison JW, et al., Rapid evolution of human pseudoautosomal genes and their mouse homologs. Mamm Genome. 1996 Jan;7(1):25-30
J:64555 Levy SE, et al., Expression and sequence analysis of the mouse adenine nucleotide translocase 1 and 2 genes. Gene. 2000 Aug 22;254(1-2):57-66
J:88165 Kokoszka JE, et al., The ADP/ATP translocator is not essential for the mitochondrial permeability transition pore. Nature. 2004 Jan 29;427(6973):461-5
J:196142 Rardin MJ, et al., Label-free quantitative proteomics of the lysine acetylome in mitochondria identifies substrates of SIRT3 in metabolic pathways. Proc Natl Acad Sci U S A. 2013 Apr 16;110(16):6601-6
J:203468 Park J, et al., SIRT5-mediated lysine desuccinylation impacts diverse metabolic pathways. Mol Cell. 2013 Jun 27;50(6):919-30
J:234617 Cho J, et al., Mitochondrial ATP transporter Ant2 depletion impairs erythropoiesis and B lymphopoiesis. Cell Death Differ. 2015 Sep;22(9):1437-50
J:287067 Karch J, et al., Inhibition of mitochondrial permeability transition by deletion of the ANT family and CypD. Sci Adv. 2019 Aug;5(8):eaaw4597
J:287489 Hoshino A, et al., The ADP/ATP translocase drives mitophagy independent of nucleotide exchange. Nature. 2019 Nov;575(7782):375-379
J:288657 Bertholet AM, et al., H(+) transport is an integral function of the mitochondrial ADP/ATP carrier. Nature. 2019 Jul;571(7766):515-520
J:292518 Huttlin EL, et al., A tissue-specific atlas of mouse protein phosphorylation and expression. Cell. 2010 Dec 23;143(7):1174-89