Sequence Detail

ID/Version

P49710 Q922I8 (UniProt | EBI)

Last sequence update: 2011-07-27
Last annotation update: 2025-02-05

Sequence description from provider

RecName: Full=Hematopoietic lineage cell-specific protein;AltName: Full=Hematopoietic cell-specific LYN substrate 1;AltName: Full=LckBP1;

Provider

SWISS-PROT

Sequence

Polypeptide 486 aa

Source

Organism mouse

See UniProt | EBI for source

Annotated genes and markers

Follow the symbol links to get more information on the GO terms, expression assays, orthologs, phenotypic alleles, and other information for the genes or markers below.

Type	Symbol	Name	GO Terms	Expression Assays	Orthologs	Phenotypic Alleles
Gene	Hcls1	hematopoietic cell specific Lyn substrate 1	65	97	3	12

Sequence references in MGI

J:24179 Kitamura D, et al., Molecular cloning and characterization of mouse HS1. Biochem Biophys Res Commun. 1995 Mar 28;208(3):1137-46
J:64960 Takemoto Y, et al., Isolation and characterization of a novel HS1 SH3 domain binding protein, HS1BP3. Int Immunol. 1999 Dec;11(12):1957-64
J:144768 McPherson VA, et al., Contributions of F-BAR and SH2 domains of Fes protein tyrosine kinase for coupling to the FcepsilonRI pathway in mast cells. Mol Cell Biol. 2009 Jan;29(2):389-401
J:148303 Samuels AL, et al., Liar, a novel Lyn-binding nuclear/cytoplasmic shuttling protein that influences erythropoietin-induced differentiation. Blood. 2009 Apr 16;113(16):3845-56
J:243407 Takemoto Y, et al., LckBP1, a proline-rich protein expressed in haematopoietic lineage cells, directly associates with the SH3 domain of protein tyrosine kinase p56lck. EMBO J. 1995 Jul 17;14(14):3403-14
J:292518 Huttlin EL, et al., A tissue-specific atlas of mouse protein phosphorylation and expression. Cell. 2010 Dec 23;143(7):1174-89