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Sequence Detail
ID/Version
P48542 P70306 P70307 Q9QYH5 P70216 P70309 P70454 O70290 P70308 (UniProt | EBI) Last sequence update: 1996-02-01
Last annotation update: 2025-02-05
Sequence
description
from provider
RecName: Full=G protein-activated inward rectifier potassium channel 2; Short=GIRK-2;AltName: Full=Inward rectifier K(+) channel Kir3.2;AltName: Full=Potassium channel, inwardly rectifying subfamily J member 6;
Provider SWISS-PROT
Sequence
Polypeptide 425 aa
For this sequence
Source
Organism mouse
See UniProt | EBI for source
Annotated genes and markers Follow the symbol links to get more information on the GO terms, expression assays, orthologs, phenotypic alleles, and other information for the genes or markers below.
Type Symbol Name GO Terms Expression
Assays
Orthologs Phenotypic
Alleles
Gene Kcnj6 potassium inwardly-rectifying channel, subfamily J, member 6 38 129 3 21
Sequence references in MGI J:29230 Patil N, et al., A potassium channel mutation in weaver mice implicates membrane excitability in granule cell differentiation [see comments]. Nat Genet. 1995 Oct;11(2):126-9
J:29320 Lesage F, et al., Cloning provides evidence for a family of inward rectifier and G-protein coupled K+ channels in the brain. FEBS Lett. 1994 Oct 10;353(1):37-42
J:29908 Lesage F, et al., Molecular properties of neuronal G-protein-activated inwardly rectifying K+ channels. J Biol Chem. 1995 Dec 1;270(48):28660-7
J:43383 Isomoto S, et al., A novel ubiquitously distributed isoform of GIRK2 (GIRK2B) enhances GIRK1 expression of the G-protein-gated K+ current in Xenopus oocytes. Biochem Biophys Res Commun. 1996 Jan 5;218(1):286-91
J:49749 Wei J, et al., Characterization of murine Girk2 transcript isoforms: structure and differential expression. Genomics. 1998 Aug 1;51(3):379-90
J:106258 Inanobe A, et al., Molecular cloning and characterization of a novel splicing variant of the Kir3.2 subunit predominantly expressed in mouse testis. J Physiol. 1999 Nov 15;521 Pt 1:19-30
J:292518 Huttlin EL, et al., A tissue-specific atlas of mouse protein phosphorylation and expression. Cell. 2010 Dec 23;143(7):1174-89
J:359363 Jelacic TM, et al., Functional expression and characterization of G-protein-gated inwardly rectifying K+ channels containing GIRK3. J Membr Biol. 1999 May 15;169(2):123-9

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
03/18/2025
MGI 6.24
The Jackson Laboratory