Sequence Detail

ID/Version

P43688 (UniProt | EBI)

Last sequence update: 1998-12-15
Last annotation update: 2025-06-18

Sequence description from provider

RecName: Full=Homeobox protein Nkx-2.6;AltName: Full=Homeobox protein NK-2 homolog F;

Provider

SWISS-PROT

Sequence

Polypeptide 289 aa

Source

Organism mouse

See UniProt | EBI for source

Annotated genes and markers

Follow the symbol links to get more information on the GO terms, expression assays, orthologs, phenotypic alleles, and other information for the genes or markers below.

Type	Symbol	Name	GO Terms	Expression Assays	Orthologs	Phenotypic Alleles
Gene	Nkx2-6	NK2 homeobox 6	43	116	3	7

Sequence references in MGI

J:15282 Lints TJ, et al., Nkx-2.5: a novel murine homeobox gene expressed in early heart progenitor cells and their myogenic descendants [published erratum appears in Development 1993 Nov;119(3):969]. Development. 1993 Oct;119(2):419-31
J:45685 Nikolova M, et al., Nkx2.6 expression is transiently and specifically restricted to the branchial region of pharyngeal-stage mouse embryos. Mech Dev. 1997 Dec;69(1-2):215-8
J:61335 Tanaka M, et al., Phenotypic characterization of the murine Nkx2.6 homeobox gene by gene targeting. Mol Cell Biol. 2000 Apr;20(8):2874-9
J:69976 Tanaka M, et al., Nkx2.5 and Nkx2.6, homologs of Drosophila tinman, are required for development of the pharynx. Mol Cell Biol. 2001 Jul;21(13):4391-8
J:143700 Biben C, et al., Expression of NK-2 class homeobox gene Nkx2-6 in foregut endoderm and heart. Mech Dev. 1998 Apr;73(1):125-7