Sequence Detail

ID/Version

P42232 Q8K3Q1 Q9JKM1 Q9R0X8 Q541Q5 A2A5D5 Q60804 (UniProt | EBI)

Last sequence update: 1995-11-01
Last annotation update: 2024-03-27

Sequence description from provider

RecName: Full=Signal transducer and activator of transcription 5B;

Provider

SWISS-PROT

Sequence

Polypeptide 786 aa

Source

Organism mouse

See UniProt | EBI for source

Annotated genes and markers

Follow the symbol links to get more information on the GO terms, expression assays, orthologs, phenotypic alleles, and other information for the genes or markers below.

Type	Symbol	Name	GO Terms	Expression Assays	Orthologs	Phenotypic Alleles
Gene	Stat5b	signal transducer and activator of transcription 5B	122	107	4	18

Sequence references in MGI

J:24359 Mui AL, et al., Interleukin-3, granulocyte-macrophage colony stimulating factor and interleukin-5 transduce signals through two STAT5 homologs. EMBO J. 1995 Mar 15;14(6):1166-75
J:29298 Liu X, et al., Cloning and expression of Stat5 and an additional homologue (Stat5b) involved in prolactin signal transduction in mouse mammary tissue. Proc Natl Acad Sci U S A. 1995 Sep 12;92(19):8831-5
J:62833 Seyfert HM, et al., Molecular characterization of STAT5A- and STAT5B-encoding genes reveals extended intragenic sequence homogeneity in cattle and mouse and different degrees of divergent evolution of various domains. J Mol Evol. 2000 Jun;50(6):550-61
J:67577 Miyoshi K, et al., Structure of the mouse stat 3/5 locus: evolution from drosophila to zebrafish to mouse. Genomics. 2001 Jan 15;71(2):150-5
J:88737 Davoodi-Semiromi A, et al., A mutant Stat5b with weaker DNA binding affinity defines a key defective pathway in nonobese diabetic mice. J Biol Chem. 2004 Mar 19;279(12):11553-61
J:99680 The FANTOM Consortium and RIKEN Genome Exploration Research Group and Genome Science Group (Genome Network Project Core Group), The Transcriptional Landscape of the Mammalian Genome. Science. 2005;309(5740):1559-1563
J:173825 Peng SC, et al., A novel role of CPEB3 in regulating EGFR gene transcription via association with Stat5b in neurons. Nucleic Acids Res. 2010 Nov 1;38(21):7446-57
J:197519 Aoki N, et al., A nuclear protein tyrosine phosphatase TC-PTP is a potential negative regulator of the PRL-mediated signaling pathway: dephosphorylation and deactivation of signal transducer and activator of transcription 5a and 5b by TC-PTP in nucleus. Mol Endocrinol. 2002 Jan;16(1):58-69
J:292518 Huttlin EL, et al., A tissue-specific atlas of mouse protein phosphorylation and expression. Cell. 2010 Dec 23;143(7):1174-89