Sequence Detail

ID/Version

P33435 (UniProt | EBI)

Last sequence update: 1994-02-01
Last annotation update: 2024-01-24

Sequence description from provider

RecName: Full=Collagenase 3; EC=3.4.24.-;AltName: Full=Matrix metalloproteinase-13; Short=MMP-13;Flags: Precursor;

Provider

SWISS-PROT

Sequence

Polypeptide 472 aa

Source

Organism mouse

See UniProt | EBI for source

Annotated genes and markers

Follow the symbol links to get more information on the GO terms, expression assays, orthologs, phenotypic alleles, and other information for the genes or markers below.

Type	Symbol	Name	GO Terms	Expression Assays	Orthologs	Phenotypic Alleles
Gene	Mmp13	matrix metallopeptidase 13	39	164	4	10

Sequence references in MGI

J:2506 Henriet P, et al., Cloning and sequencing of mouse collagenase cDNA. Divergence of mouse and rat collagenases from the other mammalian collagenases. FEBS Lett. 1992 Sep 28;310(2):175-8
J:94460 Stickens D, et al., Altered endochondral bone development in matrix metalloproteinase 13-deficient mice. Development. 2004 Dec;131(23):5883-95
J:94723 Inada M, et al., Critical roles for collagenase-3 (Mmp13) in development of growth plate cartilage and in endochondral ossification. Proc Natl Acad Sci U S A. 2004 Dec 7;101(49):17192-7
J:130351 Behonick DJ, et al., Role of Matrix Metalloproteinase 13 in Both Endochondral and Intramembranous Ossification during Skeletal Regeneration. PLoS One. 2007;2(11):e1150
J:150790 Hattori N, et al., MMP-13 plays a role in keratinocyte migration, angiogenesis, and contraction in mouse skin wound healing. Am J Pathol. 2009 Aug;175(2):533-46
J:189825 Toriseva M, et al., MMP-13 regulates growth of wound granulation tissue and modulates gene expression signatures involved in inflammation, proteolysis, and cell viability. PLoS One. 2012;7(8):e42596