Sequence Detail

ID/Version

P29319 (UniProt | EBI)

Last sequence update: 1992-12-01
Last annotation update: 2025-02-05

Sequence description from provider

RecName: Full=Ephrin type-A receptor 3; EC=2.7.10.1;AltName: Full=EPH-like kinase 4; Short=EK4; Short=mEK4;AltName: Full=Tyrosine-protein kinase TYRO4;AltName: Full=Tyrosine-protein kinase receptor ETK1;Flags: Precursor;

Provider

SWISS-PROT

Sequence

Polypeptide 983 aa

Source

Organism mouse

See UniProt | EBI for source

Annotated genes and markers

Follow the symbol links to get more information on the GO terms, expression assays, orthologs, phenotypic alleles, and other information for the genes or markers below.

Type	Symbol	Name	GO Terms	Expression Assays	Orthologs	Phenotypic Alleles
Gene	Epha3	Eph receptor A3	69	158	3	7

Sequence references in MGI

J:17817 Sajjadi FG, et al., Identification of a new eph-related receptor tyrosine kinase gene from mouse and chicken that is developmentally regulated and encodes at least two forms of the receptor. New Biol. 1991 Aug;3(8):769-78
J:86478 Vaidya A, et al., EphA3 null mutants do not demonstrate motor axon guidance defects. Mol Cell Biol. 2003 Nov;23(22):8092-8
J:119874 Stephen LJ, et al., A critical role for the EphA3 receptor tyrosine kinase in heart development. Dev Biol. 2007 Feb 1;302(1):66-79
J:133671 Gallarda BW, et al., Segregation of axial motor and sensory pathways via heterotypic trans-axonal signaling. Science. 2008 Apr 11;320(5873):233-6
J:152203 Hu T, et al., Regulation of process retraction and cell migration by EphA3 is mediated by the adaptor protein Nck1. Biochemistry. 2009 Jul 14;48(27):6369-78
J:175107 Lawrenson ID, et al., Ephrin-A5 induces rounding, blebbing and de-adhesion of EphA3-expressing 293T and melanoma cells by CrkII and Rho-mediated signalling. J Cell Sci. 2002 Mar 1;115(Pt 5):1059-72
J:241039 Alonso-Martin S, et al., Gene Expression Profiling of Muscle Stem Cells Identifies Novel Regulators of Postnatal Myogenesis. Front Cell Dev Biol. 2016;4:58