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Sequence Detail
P28334 (UniProt | EBI) Last sequence update: 1992-12-01
Last annotation update: 2019-09-18
from provider
RecName: Full=5-hydroxytryptamine receptor 1B; Short=5-HT-1B; Short=5-HT1B;AltName: Full=Serotonin receptor 1B;
Polypeptide 386 aa
For this sequence
Organism mouse
See UniProt | EBI for source
Annotated genes and markers Follow the symbol links to get more information on the GO terms, expression assays, orthologs, phenotypic alleles, and other information for the genes or markers below.
Type Symbol Name GO Terms Expression
Orthologs Phenotypic
Gene Htr1b 5-hydroxytryptamine (serotonin) receptor 1B 55 4 9 8
Sequence references in MGI J:43 Maroteaux L, et al., Mouse 5HT1B serotonin receptor: cloning, functional expression, and localization in motor control centers. Proc Natl Acad Sci U S A. 1992 Apr 1;89(7):3020-4
J:20209 Saudou F, et al., Enhanced aggressive behavior in mice lacking 5-HT1B receptor. Science. 1994 Sep 23;265(5180):1875-8
J:43716 Trillat AC, et al., Regulation of serotonin release in the frontal cortex and ventral hippocampus of homozygous mice lacking 5-HT1B receptors: in vivo microdialysis studies. J Neurochem. 1997 Nov;69(5):2019-25
J:60039 Sarhan H, et al., 5-HT1B receptors modulate release of [3H]dopamine from rat striatal synaptosomes: further evidence using 5-HT moduline, polyclonal 5-HT1B receptor antibodies and 5-HT1B receptor knock-out mice. Naunyn Schmiedebergs Arch Pharmacol. 2000 Jan;361(1):12-8
J:112765 Rutz S, et al., Presynaptic serotonergic modulation of 5-HT and acetylcholine release in the hippocampus and the cortex of 5-HT1B-receptor knockout mice. Brain Res Bull. 2006 Jun 15;70(1):81-93
J:118053 Pineyro G, et al., Regulation of [3H]5-HT release in raphe, frontal cortex and hippocampus of 5-HT1B knock-out mice. Neuroreport. 1995 Dec 29;7(1):353-9

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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
MGI 6.14
The Jackson Laboratory