Sequence Detail

ID/Version

P23819 Q61604 Q61605 Q8BG69 Q8BXU3 Q9D6D3 (UniProt | EBI)

Last sequence update: 2002-08-02
Last annotation update: 2024-03-27

Sequence description from provider

RecName: Full=Glutamate receptor 2 {ECO:0000305}; Short=GluR-2;AltName: Full=AMPA-selective glutamate receptor 2;AltName: Full=GluR-B;AltName: Full=GluR-K2;AltName: Full=Glutamate receptor ionotropic, AMPA 2; Short=GluA2;Flags: Precursor;

Provider

SWISS-PROT

Sequence

Polypeptide 883 aa

Source

Organism mouse

See UniProt | EBI for source

Annotated genes and markers

Follow the symbol links to get more information on the GO terms, expression assays, orthologs, phenotypic alleles, and other information for the genes or markers below.

Type	Symbol	Name	GO Terms	Expression Assays	Orthologs	Phenotypic Alleles
Gene	Gria2	glutamate receptor, ionotropic, AMPA2 (alpha 2)	114	124	4	28

Sequence references in MGI

J:10801 Sakimura K, et al., Functional expression from cloned cDNAs of glutamate receptor species responsive to kainate and quisqualate. FEBS Lett. 1990 Oct 15;272(1-2):73-80
J:30462 Kohler M, et al., The organization of the gene for the functionally dominant alpha-amino-3-hydroxy-5-methylisoxazole-4-propionic acid receptor subunit GluR-B. J Biol Chem. 1994 Jul 1;269(26):17367-70
J:40449 Sommer B, et al., RNA editing in brain controls a determinant of ion flow in glutamate-gated channels. Cell. 1991 Oct 4;67(1):11-9
J:81682 Stegmuller J, et al., The proteoglycan NG2 is complexed with alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid (AMPA) receptors by the PDZ glutamate receptor interaction protein (GRIP) in glial progenitor cells. Implications for glial-neuronal signaling. J Biol Chem. 2003 Feb 7;278(6):3590-8
J:87180 Kolleker A, et al., Glutamatergic plasticity by synaptic delivery of GluR-B long-containing AMPA receptors. Neuron. 2003 Dec 18;40(6):1199-212
J:99680 The FANTOM Consortium and RIKEN Genome Exploration Research Group and Genome Science Group (Genome Network Project Core Group), The Transcriptional Landscape of the Mammalian Genome. Science. 2005;309(5740):1559-1563
J:113845 Dev KK, et al., The protein kinase C alpha binding protein PICK1 interacts with short but not long form alternative splice variants of AMPA receptor subunits. Neuropharmacology. 1999 May;38(5):635-44
J:135974 Matsuda S, et al., Accumulation of AMPA receptors in autophagosomes in neuronal axons lacking adaptor protein AP-4. Neuron. 2008 Mar 13;57(5):730-45
J:158601 Kalashnikova E, et al., SynDIG1: an activity-regulated, AMPA- receptor-interacting transmembrane protein that regulates excitatory synapse development. Neuron. 2010 Jan 14;65(1):80-93
J:163183 Scholz R, et al., AMPA receptor signaling through BRAG2 and Arf6 critical for long-term synaptic depression. Neuron. 2010 Jun 10;66(5):768-80
J:173768 Zhang J, et al., The AAA+ ATPase Thorase regulates AMPA receptor-dependent synaptic plasticity and behavior. Cell. 2011 Apr 15;145(2):284-99
J:198375 Wang X, et al., Loss of sorting nexin 27 contributes to excitatory synaptic dysfunction by modulating glutamate receptor recycling in Down's syndrome. Nat Med. 2013 Apr;19(4):473-80
J:217902 Sultana A, et al., Deletion of olfactomedin 2 induces changes in the AMPA receptor complex and impairs visual, olfactory, and motor functions in mice. Exp Neurol. 2014 Nov;261:802-11
J:292518 Huttlin EL, et al., A tissue-specific atlas of mouse protein phosphorylation and expression. Cell. 2010 Dec 23;143(7):1174-89