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Sequence Detail
P23611 (UniProt | EBI) Last sequence update: 1991-11-01
Last annotation update: 2019-02-13
from provider
RecName: Full=Interferon regulatory factor 8; Short=IRF-8;AltName: Full=Interferon consensus sequence-binding protein; Short=ICSBP;
Polypeptide 424 aa
For this sequence
Organism mouse
See UniProt | EBI for source
Annotated genes and markers Follow the symbol links to get more information on the GO terms, expression assays, orthologs, phenotypic alleles, and other information for the genes or markers below.
Type Symbol Name GO Terms Expression
Orthologs Phenotypic
Gene Irf8 interferon regulatory factor 8 36 12 9 10
Sequence references in MGI J:17559 Driggers PH, et al., An interferon gamma-regulated protein that binds the interferon-inducible enhancer element of major histocompatibility complex class I genes. Proc Natl Acad Sci U S A. 1990 May;87(10):3743-7
J:99680 The FANTOM Consortium and RIKEN Genome Exploration Research Group and Genome Science Group (Genome Network Project Core Group), The Transcriptional Landscape of the Mammalian Genome. Science. 2005;309(5740):1559-1563
J:149427 Kong HJ, et al., Cutting edge: autoantigen Ro52 is an interferon inducible E3 ligase that ubiquitinates IRF-8 and enhances cytokine expression in macrophages. J Immunol. 2007 Jul 1;179(1):26-30
J:188767 Tussiwand R, et al., Compensatory dendritic cell development mediated by BATF-IRF interactions. Nature. 2012 Oct 25;490(7421):502-7

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last database update
MGI 6.14
The Jackson Laboratory