Sequence Detail

ID/Version

P20826 Q62524 Q921N5 Q3TNJ7 P97332 Q64222 (UniProt | EBI)

Last sequence update: 1991-02-01
Last annotation update: 2025-02-05

Sequence description from provider

RecName: Full=Kit ligand;AltName: Full=Hematopoietic growth factor KL;AltName: Full=Mast cell growth factor; Short=MGF;AltName: Full=Steel factor;AltName: Full=Stem cell factor; Short=SCF;AltName: Full=c-Kit ligand;Contains: RecName: Full

Provider

SWISS-PROT

Sequence

Polypeptide 273 aa

Source

Organism mouse

See UniProt | EBI for source

Annotated genes and markers

Follow the symbol links to get more information on the GO terms, expression assays, orthologs, phenotypic alleles, and other information for the genes or markers below.

Type	Symbol	Name	GO Terms	Expression Assays	Orthologs	Phenotypic Alleles
Gene	Kitl	kit ligand	85	170	4	83

Sequence references in MGI

J:1527 Huang EJ, et al., Differential expression and processing of two cell associated forms of the kit-ligand: KL-1 and KL-2. Mol Biol Cell. 1992 Mar;3(3):349-62
J:2880 Brannan CI, et al., Developmental abnormalities in Steel17H mice result from a splicing defect in the steel factor cytoplasmic tail. Genes Dev. 1992 Oct;6(10):1832-42
J:10747 Williams DE, et al., Identification of a ligand for the c-kit proto-oncogene. Cell. 1990 Oct 5;63(1):167-74
J:10748 Copeland NG, et al., Mast cell growth factor maps near the steel locus on mouse chromosome 10 and is deleted in a number of steel alleles. Cell. 1990 Oct 5;63(1):175-83
J:10750 Zsebo KM, et al., Stem cell factor is encoded at the Sl locus of the mouse and is the ligand for the c-kit tyrosine kinase receptor. Cell. 1990 Oct 5;63(1):213-24
J:10751 Huang E, et al., The hematopoietic growth factor KL is encoded by the Sl locus and is the ligand of the c-kit receptor, the gene product of the W locus. Cell. 1990 Oct 5;63(1):225-33
J:10752 Anderson DM, et al., Molecular cloning of mast cell growth factor, a hematopoietin that is active in both membrane bound and soluble forms [published erratum appears in Cell 1990 Nov 30;63(5):following 1112]. Cell. 1990 Oct 5;63(1):235-43
J:31565 Bedell MA, et al., Multiple pathways for Steel regulation suggested by genomic and sequence analysis of the murine Steel gene. Genetics. 1996 Mar;142(3):927-34
J:37172 Graw J, et al., Molecular analysis of two new Steel mutations in mice shows a transversion or an insertion. Mamm Genome. 1996 Nov;7(11):843-6
J:40339 Flanagan JG, et al., Transmembrane form of the kit ligand growth factor is determined by alternative splicing and is missing in the Sld mutant. Cell. 1991 Mar 8;64(5):1025-35
J:43966 Graw J, et al., Detection of a point mutation (A to G) in exon 5 of the murine Mgf gene defines a novel allele at the Steel locus with a weak phenotype. Mutat Res. 1997 Sep;382(1-2):75-8
J:99680 The FANTOM Consortium and RIKEN Genome Exploration Research Group and Genome Science Group (Genome Network Project Core Group), The Transcriptional Landscape of the Mammalian Genome. Science. 2005;309(5740):1559-1563