Sequence Detail

ID/Version

P17553 (UniProt | EBI)

Last sequence update: 1990-08-01
Last annotation update: 2025-02-05

Sequence description from provider

RecName: Full=Proto-oncogene Wnt-3;AltName: Full=Proto-oncogene Int-4;Flags: Precursor;

Provider

SWISS-PROT

Sequence

Polypeptide 355 aa

Source

Organism mouse

See UniProt | EBI for source

Annotated genes and markers

Follow the symbol links to get more information on the GO terms, expression assays, orthologs, phenotypic alleles, and other information for the genes or markers below.

Type	Symbol	Name	GO Terms	Expression Assays	Orthologs	Phenotypic Alleles
Gene	Wnt3	wingless-type MMTV integration site family, member 3	70	173	3	18

Sequence references in MGI

J:10554 Roelink H, et al., Wnt-3, a gene activated by proviral insertion in mouse mammary tumors, is homologous to int-1/Wnt-1 and is normally expressed in mouse embryos and adult brain. Proc Natl Acad Sci U S A. 1990 Jun;87(12):4519-23
J:56511 Liu P, et al., Requirement for Wnt3 in vertebrate axis formation. Nat Genet. 1999 Aug;22(4):361-5
J:63226 Tanaka K, et al., The evolutionarily conserved porcupine gene family is involved in the processing of the Wnt family. Eur J Biochem. 2000 Jul;267(13):4300-11
J:81795 Barrow JR, et al., Ectodermal Wnt3/beta-catenin signaling is required for the establishment and maintenance of the apical ectodermal ridge. Genes Dev. 2003 Feb 1;17(3):394-409
J:154679 Fu J, et al., Reciprocal regulation of Wnt and Gpr177/mouse Wntless is required for embryonic axis formation. Proc Natl Acad Sci U S A. 2009 Nov 3;106(44):18598-603