Sequence Detail

ID/Version

P16879 Q3TD20 Q8CG02 Q62122 (UniProt | EBI)

Last sequence update: 2008-01-15
Last annotation update: 2025-02-05

Sequence description from provider

RecName: Full=Tyrosine-protein kinase Fes/Fps; EC=2.7.10.2;AltName: Full=Proto-oncogene c-Fes;

Provider

SWISS-PROT

Sequence

Polypeptide 822 aa

Source

Organism mouse

See UniProt | EBI for source

Annotated genes and markers

Follow the symbol links to get more information on the GO terms, expression assays, orthologs, phenotypic alleles, and other information for the genes or markers below.

Type	Symbol	Name	GO Terms	Expression Assays	Orthologs	Phenotypic Alleles
Gene	Fes	feline sarcoma oncogene	101	97	3	12

Sequence references in MGI

J:9517 Wilks AF, et al., Isolation and structural analysis of murine c-fes cDNA clones. Oncogene. 1988 Sep;3(3):289-94
J:22689 Wilks AF, et al., The application of the polymerase chain reaction to cloning members of the protein tyrosine kinase family. Gene. 1989 Dec 21;85(1):67-74
J:84866 Senis YA, et al., Fps/Fes and Fer protein-tyrosinekinases play redundant roles in regulating hematopoiesis. Exp Hematol. 2003 Aug;31(8):673-81
J:98590 Zirngibl RA, et al., Enhanced endotoxin sensitivity in fps/fes-null mice with minimal defects in hematopoietic homeostasis. Mol Cell Biol. 2002 Apr;22(8):2472-86
J:99680 The FANTOM Consortium and RIKEN Genome Exploration Research Group and Genome Science Group (Genome Network Project Core Group), The Transcriptional Landscape of the Mammalian Genome. Science. 2005;309(5740):1559-1563
J:116450 Udell CM, et al., Fer and Fps/Fes participate in a Lyn-dependent pathway from FcepsilonRI to platelet-endothelial cell adhesion molecule 1 to limit mast cell activation. J Biol Chem. 2006 Jul 28;281(30):20949-57
J:244758 Olvedy M, et al., Comparative oncogenomics identifies tyrosine kinase FES as a tumor suppressor in melanoma. J Clin Invest. 2017 Jun 01;127(6):2310-2325