Sequence Detail

ID/Version

P15535 (UniProt | EBI)

Last sequence update: 1990-04-01
Last annotation update: 2024-03-27

Sequence description from provider

RecName: Full=Beta-1,4-galactosyltransferase 1 {ECO:0000305}; Short=Beta-1,4-GalTase 1; Short=Beta4Gal-T1; Short=b4Gal-T1; EC=2.4.1.-;AltName: Full=Beta-N-acetylglucosaminyl-glycolipid beta-1,4-galactosyltransferase;AltName

Provider

SWISS-PROT

Sequence

Polypeptide 399 aa

Source

Organism mouse

See UniProt | EBI for source

Annotated genes and markers

Follow the symbol links to get more information on the GO terms, expression assays, orthologs, phenotypic alleles, and other information for the genes or markers below.

Type	Symbol	Name	GO Terms	Expression Assays	Orthologs	Phenotypic Alleles
Gene	B4galt1	UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 1	85	103	3	63

Sequence references in MGI

J:9248 Shaper NL, et al., Characterization of the full length cDNA for murine beta-1,4-galactosyltransferase. Novel features at the 5'-end predict two translational start sites at two in-frame AUGs. J Biol Chem. 1988 Jul 25;263(21):10420-8
J:9943 Hollis GF, et al., Genomic structure of murine beta-1,4-galactosyltransferase. Biochem Biophys Res Commun. 1989 Aug 15;162(3):1069-75
J:10279 Shaper NL, et al., Murine beta 1,4-galactosyltransferase: both the amounts and structure of the mRNA are regulated during spermatogenesis. Proc Natl Acad Sci U S A. 1990 Jan;87(2):791-5
J:21408 Harduin-Lepers A, et al., Murine beta 1,4-galactosyltransferase: round spermatid transcripts are characterized by an extended 5'-untranslated region. Glycobiology. 1992 Aug;2(4):361-8
J:41033 Nakazawa K, et al., Cloning and sequencing of a full-length cDNA of mouse N-acetylglucosamine (beta 1-4)galactosyltransferase. J Biochem. 1988 Aug;104(2):165-8
J:67774 Nakamura N, et al., Differential gene expression of beta-1,4-galactosyltransferases I, II and V during mouse brain development. J Neurochem. 2001 Jan;76(1):29-38
J:214717 Wassler MJ, et al., Characterization of a novel ubiquitin-conjugating enzyme that regulates beta1,4-galactosyltransferase-1 in embryonic stem cells. Stem Cells. 2008 Aug;26(8):2006-18
J:292518 Huttlin EL, et al., A tissue-specific atlas of mouse protein phosphorylation and expression. Cell. 2010 Dec 23;143(7):1174-89
J:317226 Montasser ME, et al., Genetic and functional evidence links a missense variant in B4GALT1 to lower LDL and fibrinogen. Science. 2021 Dec 3;374(6572):1221-1227