Sequence Detail

ID/Version

O35491 E9Q721 (UniProt | EBI)

Last sequence update: 2011-07-27
Last annotation update: 2025-02-05

Sequence description from provider

RecName: Full=Dual specificity protein kinase CLK2; EC=2.7.12.1;AltName: Full=CDC-like kinase 2;

Provider

SWISS-PROT

Sequence

Polypeptide 499 aa

Source

Organism mouse

See UniProt | EBI for source

Annotated genes and markers

Follow the symbol links to get more information on the GO terms, expression assays, orthologs, phenotypic alleles, and other information for the genes or markers below.

Type	Symbol	Name	GO Terms	Expression Assays	Orthologs	Phenotypic Alleles
Gene	Clk2	CDC-like kinase 2	36	98	5	14

Sequence references in MGI

J:43003 Nayler O, et al., Characterization and comparison of four serine- and arginine-rich (SR) protein kinases. Biochem J. 1997 Sep 15;326(Pt 3):693-700
J:157003 Rodgers JT, et al., Cdc2-like kinase 2 is an insulin-regulated suppressor of hepatic gluconeogenesis. Cell Metab. 2010 Jan;11(1):23-34
J:170849 Rodgers JT, et al., Clk2 and B56beta mediate insulin-regulated assembly of the PP2A phosphatase holoenzyme complex on Akt. Mol Cell. 2011 Feb 18;41(4):471-9
J:177176 Nayler O, et al., The cellular localization of the murine serine/arginine-rich protein kinase CLK2 is regulated by serine 141 autophosphorylation. J Biol Chem. 1998 Dec 18;273(51):34341-8
J:292518 Huttlin EL, et al., A tissue-specific atlas of mouse protein phosphorylation and expression. Cell. 2010 Dec 23;143(7):1174-89