About   Help   FAQ
Sequence Detail
ID/Version
O35449 (UniProt | EBI) Last sequence update: 1998-01-01
Last annotation update: 2025-02-05
Sequence
description
from provider
RecName: Full=Proline-rich transmembrane protein 1;AltName: Full=Dispanin subfamily D member 1; Short=DSPD1;AltName: Full=Synapse differentiation-induced protein 4 {ECO:0000303|PubMed:29490264}; Short=SynDIG4 {ECO:0000303|PubMed:29490264};
Provider SWISS-PROT
Sequence
Polypeptide 306 aa
For this sequence
Source
Organism mouse
See UniProt | EBI for source
Annotated genes and markers Follow the symbol links to get more information on the GO terms, expression assays, orthologs, phenotypic alleles, and other information for the genes or markers below.
Type Symbol Name GO Terms Expression
Assays
Orthologs Phenotypic
Alleles
Gene Prrt1 proline-rich transmembrane protein 1 23 96 3 2
Sequence references in MGI J:86796 Xie T, et al., Analysis of the gene-dense Major Histocompatibility Complex class III region and its comparison to mouse. Genome Res. 2003 Dec;13(12):2621-36
J:188364 Schwenk J, et al., High-resolution proteomics unravel architecture and molecular diversity of native AMPA receptor complexes. Neuron. 2012 May 24;74(4):621-33
J:260353 Matt L, et al., SynDIG4/Prrt1 Is Required for Excitatory Synapse Development and Plasticity Underlying Cognitive Function. Cell Rep. 2018 Feb 27;22(9):2246-2253
J:291351 Troyano-Rodriguez E, et al., PRRT1 regulates basal and plasticity-induced AMPA receptor trafficking. Mol Cell Neurosci. 2019 Jul;98:155-163
J:292518 Huttlin EL, et al., A tissue-specific atlas of mouse protein phosphorylation and expression. Cell. 2010 Dec 23;143(7):1174-89

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support.
last database update
03/18/2025
MGI 6.24
The Jackson Laboratory