Sequence Detail

ID/Version

O08528 (UniProt | EBI)

Last sequence update: 1997-07-01
Last annotation update: 2025-02-05

Sequence description from provider

RecName: Full=Hexokinase-2 {ECO:0000305}; EC=2.7.1.1 {ECO:0000250|UniProtKB:P52789};AltName: Full=Hexokinase type II {ECO:0000303|PubMed:15489334}; Short=HK II {ECO:0000303|PubMed:15489334};

Provider

SWISS-PROT

Sequence

Polypeptide 917 aa

Source

Organism mouse

See UniProt | EBI for source

Annotated genes and markers

Follow the symbol links to get more information on the GO terms, expression assays, orthologs, phenotypic alleles, and other information for the genes or markers below.

Type	Symbol	Name	GO Terms	Expression Assays	Orthologs	Phenotypic Alleles
Gene	Hk2	hexokinase 2	98	117	3	55

Sequence references in MGI

J:56644 Heikkinen S, et al., Hexokinase II-deficient mice. Prenatal death of homozygotes without disturbances in glucose tolerance in heterozygotes. J Biol Chem. 1999 Aug 6;274(32):22517-23
J:59905 Heikkinen S, et al., Mouse hexokinase II gene: structure, cDNA, promoter analysis, and expression pattern. Mamm Genome. 2000 Feb;11(2):91-6
J:133172 Chiara F, et al., Hexokinase II detachment from mitochondria triggers apoptosis through the permeability transition pore independent of voltage-dependent anion channels. PLoS One. 2008;3(3):e1852
J:292518 Huttlin EL, et al., A tissue-specific atlas of mouse protein phosphorylation and expression. Cell. 2010 Dec 23;143(7):1174-89