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Sequence Detail
A2ARA8 O70304 Q8BRG3 Q8C0H7 Q3UXV8 (UniProt | EBI) Last sequence update: 2007-02-20
Last annotation update: 2019-02-13
from provider
RecName: Full=Integrin alpha-8;Contains: RecName: Full=Integrin alpha-8 heavy chain;Contains: RecName: Full=Integrin alpha-8 light chain;Flags: Precursor;
Polypeptide 1062 aa
For this sequence
Organism mouse
See UniProt | EBI for source
Annotated genes and markers Follow the symbol links to get more information on the GO terms, expression assays, orthologs, phenotypic alleles, and other information for the genes or markers below.
Type Symbol Name GO Terms Expression
Orthologs Phenotypic
Gene Itga8 integrin alpha 8 31 7 8 5
Sequence references in MGI J:38838 Muller U, et al., Integrin alpha8beta1 is critically important for epithelial-mesenchymal interactions during kidney morphogenesis. Cell. 1997 Mar 7;88(5):603-13
J:61486 Littlewood Evans A, et al., Stereocilia defects in the sensory hair cells of the inner ear in mice deficient in integrin alpha8beta1. Nat Genet. 2000 Apr;24(4):424-8
J:70545 Brandenberger R, et al., Identification and characterization of a novel extracellular matrix protein nephronectin that is associated with integrin alpha8beta1 in the embryonic kidney. J Cell Biol. 2001 Jul 23;154(2):447-58
J:85775 Wagner TE, et al., Expression of the integrin subunit alpha8 in murine lung development. J Histochem Cytochem. 2003 Oct;51(10):1307-15
J:99680 The FANTOM Consortium and RIKEN Genome Exploration Research Group and Genome Science Group (Genome Network Project Core Group), The Transcriptional Landscape of the Mammalian Genome. Science. 2005;309(5740):1559-1563
J:122519 Linton JM, et al., The ECM protein nephronectin promotes kidney development via integrin {alpha}8{beta}1-mediated stimulation of Gdnf expression. Development. 2007 Jul;134(13):2501-9

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
MGI 6.13
The Jackson Laboratory