Sequence Detail

ID/Version

A2AJ77 (UniProt | EBI)

Last sequence update: 2007-02-20
Last annotation update: 2025-06-18

Sequence description from provider

RecName: Full=PR domain zinc finger protein 12;AltName: Full=PR domain-containing protein 12;

Provider

SWISS-PROT

Sequence

Polypeptide 365 aa

Source

Organism mouse

See UniProt | EBI for source

Annotated genes and markers

Follow the symbol links to get more information on the GO terms, expression assays, orthologs, phenotypic alleles, and other information for the genes or markers below.

Type	Symbol	Name	GO Terms	Expression Assays	Orthologs	Phenotypic Alleles
Gene	Prdm12	PR domain containing 12	38	108	4	12

Sequence references in MGI

J:231782 Chen YC, et al., Transcriptional regulator PRDM12 is essential for human pain perception. Nat Genet. 2015 Jul;47(7):803-8
J:288459 Bartesaghi L, et al., PRDM12 Is Required for Initiation of the Nociceptive Neuron Lineage during Neurogenesis. Cell Rep. 2019 Mar 26;26(13):3484-3492.e4
J:304297 Landy MA, et al., Loss of Prdm12 during development, but not in mature nociceptors, causes defects in pain sensation. Cell Rep. 2021 Mar 30;34(13):108913
J:330428 Latragna A, et al., Prdm12 modulates pain-related behavior by remodeling gene expression in mature nociceptors. Pain. 2022 Aug 1;163(8):e927-e941