Sequence Detail

ID/Version

A2AF47 Q5KTP7 (UniProt | EBI)

Last sequence update: 2007-02-20
Last annotation update: 2025-02-05

Sequence description from provider

RecName: Full=Dedicator of cytokinesis protein 11 {ECO:0000312|MGI:MGI:1923224};AltName: Full=Activated Cdc42-associated guanine nucleotide exchange factor; Short=ACG;AltName: Full=Zizimin-2 {ECO:0000303|PubMed:25729399};

Provider

SWISS-PROT

Sequence

Polypeptide 2073 aa

Source

Organism mouse

See UniProt | EBI for source

Annotated genes and markers

Follow the symbol links to get more information on the GO terms, expression assays, orthologs, phenotypic alleles, and other information for the genes or markers below.

Type	Symbol	Name	GO Terms	Expression Assays	Orthologs	Phenotypic Alleles
Gene	Dock11	dedicator of cytokinesis 11	15	97	3	10

Sequence references in MGI

J:96146 Nishikimi A, et al., Zizimin2: a novel, DOCK180-related Cdc42 guanine nucleotide exchange factor expressed predominantly in lymphocytes. FEBS Lett. 2005 Feb 14;579(5):1039-46
J:238172 Matsuda T, et al., The immunosenescence-related gene Zizimin2 is associated with early bone marrow B cell development and marginal zone B cell formation. Immun Ageing. 2015;12:1
J:239194 Jaudon F, et al., The RhoGEF DOCK10 is essential for dendritic spine morphogenesis. Mol Biol Cell. 2015 Jun 01;26(11):2112-27
J:239198 Sakabe I, et al., Age-related guanine nucleotide exchange factor, mouse Zizimin2, induces filopodia in bone marrow-derived dendritic cells. Immun Ageing. 2012 Apr 11;9:2
J:292518 Huttlin EL, et al., A tissue-specific atlas of mouse protein phosphorylation and expression. Cell. 2010 Dec 23;143(7):1174-89