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Tg(Prrx1-mTFP1,-cre/ERT2)1Etnka - Limbs
Recombinase Activity Detail
Allele Information
Allele:
Tg(Prrx1-mTFP1,-cre/ERT2)1Etnka
transgene insertion 1, Elly M Tanaka 		Driver: Prrx1
Type: Transgenic (Inducible, Recombinase, Reporter)
Inducer: tamoxifen
Synonym: Prrx1 enhancer-CreER-T2A-mTFPnls, Prrx1enh-CreER
Molecular description: A transgene consists of the 2.4 kb mouse Prrx1 enhancer followed by the b-globin intron and nuclear-localized teal fluorescent protein-1 (mTFP1-nls), a T2A self-cleaving peptide, and CreERT2. Six founder animals were generated and a single line with the ability to induce the recombination of LoxP reporter lines only after administration of tamoxifen was established and used for the studies.
Find mice (IMSR): Mouse Strains: 0 strains available       Cell Lines: 0 lines available
Additional Tissues: Tg(Prrx1-mTFP1,-cre/ERT2)1Etnka activity also observed in:
embryo-other, head, integumental system, mesenchyme
Tissue Information
Limbs Other recombinase alleles with activity in Limbs tissues:
Images
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J:337818 Fig. 2 J:337818 Fig. 3
Recombinase Activity
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Assays Genotypic Background Result Notes  
References
All for this allele: 1 reference(s)
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Funding Information
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Send questions and comments to User Support. 		last database update
04/23/2024
MGI 6.23 		The Jackson Laboratory