Tg(Prrx1-mTFP1,-cre/ERT2)1Etnka
Transgene Detail
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Symbol: |
Tg(Prrx1-mTFP1,-cre/ERT2)1Etnka |
Name: |
transgene insertion 1, Elly M Tanaka |
MGI ID: |
MGI:7507547 |
Synonyms: |
Prrx1 enhancer-CreER-T2A-mTFPnls, Prrx1enh-CreER |
Transgene: |
Tg(Prrx1-mTFP1,-cre/ERT2)1Etnka Location: unknown
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Alliance: |
Tg(Prrx1-mTFP1,-cre/ERT2)1Etnka page
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Transgene Type: |
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Transgenic (Inducible, Recombinase, Reporter) |
Inducer: |
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tamoxifen |
Mutation: |
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Insertion
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Tg(Prrx1-mTFP1,-cre/ERT2)1Etnka expression driven by
1 gene
Transgene expression driven by:
Organism |
Driver Gene |
Note |
mouse |
Prrx1 (MGI:97712) |
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Mutation details: A transgene consists of the 2.4 kb mouse Prrx1 enhancer followed by the b-globin intron and nuclear-localized teal fluorescent protein-1 (mTFP1-nls), a T2A self-cleaving peptide, and CreERT2. Six founder animals were generated and a single line with the ability to induce the recombination of LoxP reporter lines only after administration of tamoxifen was established and used for the studies.
(J:337818)
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Activity: |
Tissue activity of this recombinase allele
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Driver:
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Prrx1
(mouse)
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Mouse strains and cell lines
available from the International Mouse Strain Resource
(IMSR) |
Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available
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Original: |
J:337818 Currie JD, et al., The Prrx1 limb enhancer marks an adult subpopulation of injury-responsive dermal fibroblasts. Biol Open. 2019;8(7):bio043711 |
All: |
1 reference(s) |
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