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Abcg2tm1.1(cre/Esr1*)Jvbe - Cardiovascular System
Recombinase Activity Detail
Allele Information
Allele:
Abcg2tm1.1(cre/Esr1*)Jvbe
ATP binding cassette subfamily G member 2 (Junior blood group); targeted mutation 1.1, Jop H van Berlo
Driver: Abcg2
Type: Targeted (Inducible, Recombinase)
Inducer: tamoxifen
Synonym: Abcg2MCM
Molecular description: A cDNA encoding MerCreMer (cre recombinase fused to two modified estrogen receptor ligand binding domains at both ends), and an frt-flanked neomycin selection cassette were cloned in-frame with the Acbdg2 ATG start codon containing a second exon of Abcg2. Homologous recombination was performed in ES cells, and chimeras were bred to flp-expressing knock-in mice to delete the selection marker.
Find mice (IMSR): Mouse Strains: 0 strains available       Cell Lines: 0 lines available
Additional Tissues: Abcg2tm1.1(cre/Esr1*)Jvbe activity also observed in:
Tissue Information
Cardiovascular System Other recombinase alleles with activity in Cardiovascular System tissues:
Recombinase Activity
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Assays Genotypic Background Result Notes  
References
All for this allele: 1 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
04/23/2024
MGI 6.23
The Jackson Laboratory