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Sfrp5em1.1(ERT2/cre)Kkb - Cardiovascular System
Recombinase Activity Detail
Allele Information
Allele:
Sfrp5em1.1(ERT2/cre)Kkb
secreted frizzled-related sequence protein 5; endonuclease-mediated mutation 1.1, Hiroki Kokubo 		Driver: Sfrp5
Type: Endonuclease-mediated (Inducible, Recombinase)
Inducer: tamoxifen
Synonym: Sfrp5-ERT2Cre
Molecular description: A targeting vector consisting of a cassette containing ERT2-Cre-recombinase genes with frt-PGK-neomycin (neo)-bpA-frt was used for homologous recombination in ES cells using the CRISPR-Cas9 system to replace the exon 1 of the Sfrp5 gene. Frt-neo was then removed by crossing with Rosa-Flp mice.
Find mice (IMSR): Mouse Strains: 1 strain available       Cell Lines: 0 lines available
Tissue Information
Cardiovascular System Other recombinase alleles with activity in Cardiovascular System tissues:
Images
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J:245018 Fig. 3
Recombinase Activity
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Assays Genotypic Background Result Notes  
References
All for this allele: 1 reference(s)
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Funding Information
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Send questions and comments to User Support. 		last database update
04/23/2024
MGI 6.23 		The Jackson Laboratory